Votion Dominique-M, Serteyn Didier
Equine Teaching Hospital, Department of Clinical Sciences, Faculty of Veterinary Medicine, University of Liège, 4000 Liège, Belgium.
Vet J. 2008 Nov;178(2):185-90. doi: 10.1016/j.tvjl.2008.02.004. Epub 2008 Mar 28.
Atypical myopathy (AM) is an acute rhabdomyolysis syndrome that occurs at irregular intervals in grazing equines. An increasing number of outbreaks have been reported in recent years, including some from countries where the disease has not previously been diagnosed. In this review, clinical and other details of outbreaks of AM are analysed to better define its epidemiological profile. Potential aetiologies are discussed, the short clinical course of AM is described and the main biochemical and pathological findings are considered. Recommendations for medical management are suggested, based on a review of clinical reports. Biochemical and histopathological findings have been integrated in order to characterise the physiopathology of AM. There is an ongoing requirement to record new cases of this syndrome, ideally through an epidemiological network.
非典型肌病（AM）是一种急性横纹肌溶解综合征，在放牧的马属动物中不定期发生。近年来报告的疫情越来越多，包括一些来自以前未诊断出该疾病的国家。在本综述中，分析了AM疫情的临床和其他细节，以更好地界定其流行病学特征。讨论了潜在病因，描述了AM的短临床病程，并考虑了主要的生化和病理发现。基于临床报告的综述，提出了医疗管理建议。整合了生化和组织病理学发现，以描述AM的生理病理学特征。持续需要记录该综合征的新病例，理想情况下通过流行病学网络进行记录。
