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非典型肌病:2009年秋季至2010年春季荷兰疫情回顾与描述

Atypical myopathy: a review and description of the outbreak in the Netherlands during autumn 2009 and spring 2010.

作者信息

Sas A M C, van der Kolk J H, Dank M, Westermann C M

机构信息

Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands.

出版信息

Tijdschr Diergeneeskd. 2012 Aug 1;137(8):514-21.

PMID:22930982
Abstract

This article reviews the literature on equine atypical myopathy (AM), an acute, severe rhabdomyolysis that occurs in horses at pasture. The prevalence, mortality, clinical signs, pathology, potential aetiology, typical aspects, diagnosis, treatment, and prognosis are described. Horse management, characteristic weather conditions, and possible preventive measures are also discussed. In addition, the characteristics of 54 highly probable or confirmed cases of equine AM occurring between autumn 2009 (27 cases) and spring 2010 (27 cases) in the Netherlands are described. Of the 54 affected horses, nineteen were mares, eleven geldings, and eight stallions; the sex of the other sixteen horses was not recorded. The mortality rate (74.5%) was in the same range as that reported in earlier studies. Many cases were reported at about the same time. Thirty-five horses had been pastured near maple trees, and in fifteen cases the maple trees were known to be infected with the fungus Rhytisma acerinum.

摘要

本文综述了有关马属动物非典型肌病(AM)的文献,这是一种发生在放牧马匹中的急性、严重横纹肌溶解症。文中描述了其患病率、死亡率、临床症状、病理学、潜在病因、典型特征、诊断、治疗及预后情况。还讨论了马匹管理、特征性天气条件及可能的预防措施。此外,还描述了2009年秋季(27例)至2010年春季(27例)在荷兰发生的54例高度疑似或确诊的马属动物AM病例的特征。在这54匹患病马匹中,19匹为母马,11匹为公马,8匹为种马;其他16匹马的性别未记录。死亡率(74.5%)与早期研究报告的范围相同。许多病例在大约同一时间被报告。35匹马曾在枫树附近放牧,其中15例已知枫树感染了槭树痂囊腔菌。

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引用本文的文献

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Hypoglycin A Concentrations in Maple Tree Species in the Netherlands and the Occurrence of Atypical Myopathy in Horses.荷兰枫树品种中的低血糖素A浓度与马的非典型肌病的发生情况
J Vet Intern Med. 2016 May;30(3):880-4. doi: 10.1111/jvim.13927. Epub 2016 Mar 20.
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Reference values for amino acids and acylcarnitines in peripheral blood in Quarter horses and American Miniature horses.四分之一马和美国迷你马外周血中氨基酸和酰基肉碱的参考值。
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