Lutale J K, Justesen A, Lema R S, Swai A B, McLarty D G
Department of Medicine, Muhimbili Medical Centre, University of Dar es Salaam, Tanzania.
Diabet Med. 1991 Nov;8(9):881-4. doi: 10.1111/j.1464-5491.1991.tb02129.x.
Between 1 June 1986 and 31 August 1987 all 47 pregnant diabetic Tanzanian women attending Muhimbili Medical Centre, Dar es Salaam were seen and managed by a small team of interested physicians and obstetricians. Of the 50 pregnancies there were 44 (88%) live births, five (10%) perinatal deaths, and one (2%) spontaneous abortion. One child was born with a serious congenital abnormality. All five perinatal deaths were seen in women who presented late in pregnancy (three) or had poor blood glucose control (two). In 10 (36%) of the 28 pregnancies in the 25 patients with insulin-requiring diabetes, insulin requirements decreased greater than 8 U during the course of pregnancy. The present study suggests that with close supervision of the pregnant diabetic patient in Africa perinatal mortality rates approaching those seen in developed countries can be achieved, despite the lack of home blood glucose monitoring. Rates could be further reduced if medical services were more widely available, and if all patients were educated on the importance of early presentation in pregnancy.
1986年6月1日至1987年8月31日期间,达累斯萨拉姆的穆希姆比利医疗中心对47名患有糖尿病的坦桑尼亚孕妇进行了诊治,由一小队感兴趣的内科医生和产科医生负责。在这50次妊娠中,有44例(88%)活产,5例(10%)围产期死亡,1例(2%)自然流产。有1名婴儿出生时患有严重先天性异常。所有5例围产期死亡均见于妊娠晚期就诊的妇女(3例)或血糖控制不佳的妇女(2例)。在25例需要胰岛素治疗的糖尿病患者的28次妊娠中,有10例(36%)在妊娠期间胰岛素需求量减少超过8单位。本研究表明,在非洲,尽管缺乏家庭血糖监测,但对妊娠糖尿病患者进行密切监测,仍可实现接近发达国家的围产期死亡率。如果医疗服务更广泛普及,并且所有患者都接受关于妊娠早期就诊重要性的教育,死亡率可能会进一步降低。