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一项关于评估糖尿病干预措施的系统评价综述:关注生活质量与差异。

A review of systematic reviews evaluating diabetes interventions: focus on quality of life and disparities.

作者信息

Magwood Gayenell S, Zapka Jane, Jenkins Carolyn

机构信息

The College of Nursing, Medical University of South Carolina, Charleston (GSM, JZ, CJ)

The Department of Biostatistics, Bioinformatics and Epidemiology, Medical University of South Carolina, Charleston (JZ)

出版信息

Diabetes Educ. 2008 Mar-Apr;34(2):242-65. doi: 10.1177/0145721708316551.

Abstract

PURPOSE

This article reviews the literature on definitions and issues related to measurement of quality of life in people with diabetes and summarizes reviews of evidence of intervention studies, with a particular focus on interventions targeted for underserved and minority populations.

METHODS

An integrative literature review of reviews was conducted on adult diabetes interventions and outcomes. Five electronic databases were searched. Eligible publications were those published between 1999 and 2006 that described outcome measures. Twelve review articles are included.

RESULTS

Review studies were heterogeneous in terms of intervention type, content, participants, setting, and outcome measures. Interventions used variable operational definitions and frequently lacked adequate description; therefore, comparisons of findings proved difficult. A clinical outcome, A1C, was the most frequently assessed, with little inclusion of quality-of-life measures. Several reviews and independent studies did not explicitly consider interventions aimed at the underserved. When quality of life was considered, measures and operational definition of domains were limited.

CONCLUSIONS

Understanding the relationship between interventions and resulting outcomes, particularly quality of life, will require attention to operational definitions and better conceptual models. There is an evidence base emerging about important characteristics of effective intervention programs. This evidence base can guide public health and clinical program planners to better understand and make prudent decisions about assessment, planning, implementation, and evaluation of interventions for people with complex chronic illnesses such as diabetes.

摘要

目的

本文回顾了关于糖尿病患者生活质量测量的定义及相关问题的文献,并总结了干预研究证据的综述,特别关注针对服务不足人群和少数族裔人群的干预措施。

方法

对成人糖尿病干预措施及结果进行了综述性文献整合回顾。检索了五个电子数据库。符合条件的出版物为1999年至2006年间发表的描述结果测量的文献。纳入了12篇综述文章。

结果

综述研究在干预类型、内容、参与者、环境和结果测量方面存在异质性。干预措施使用了不同的操作定义,且常常缺乏充分描述;因此,研究结果的比较很困难。临床结局糖化血红蛋白(A1C)是最常评估的指标,很少纳入生活质量测量。一些综述和独立研究没有明确考虑针对服务不足人群的干预措施。在考虑生活质量时,领域的测量和操作定义有限。

结论

要理解干预措施与所产生结果之间的关系,尤其是生活质量方面的关系,需要关注操作定义和更好的概念模型。关于有效干预项目的重要特征正在形成一个证据基础。这一证据基础可指导公共卫生和临床项目规划者更好地理解并就糖尿病等复杂慢性病患者干预措施的评估、规划、实施和评价做出审慎决策。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/edd0/4014006/53e6e0a9a1b5/nihms-328133-f0001.jpg

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