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伊拉克自由行动中院前止血带的使用:对出血控制及预后的影响

Prehospital tourniquet use in Operation Iraqi Freedom: effect on hemorrhage control and outcomes.

作者信息

Beekley Alec C, Sebesta James A, Blackbourne Lorne H, Herbert Garth S, Kauvar David S, Baer David G, Walters Thomas J, Mullenix Philip S, Holcomb John B

机构信息

Department of General Surgery, Madigan Army Medical Center, Fort Lewis, WA 98431-1100, USA.

出版信息

J Trauma. 2008 Feb;64(2 Suppl):S28-37; discussion S37. doi: 10.1097/TA.0b013e318160937e.

Abstract

BACKGROUND

Up to 9% of casualties killed in action during the Vietnam War died from exsanguination from extremity injuries. Retrospective reviews of prehospital tourniquet use in World War II and by the Israeli Defense Forces revealed improvements in extremity hemorrhage control and very few adverse limb outcomes when tourniquet times are less than 6 hours.

HYPOTHESIS

We hypothesized that prehospital tourniquet use decreased hemorrhage from extremity injuries and saved lives, and was not associated with a substantial increase in adverse limb outcomes.

METHODS

This was an institutional review board-approved, retrospective review of the 31st combat support hospital for 1 year during Operation Iraqi Freedom. Inclusion criteria were any patient with a traumatic amputation, major extremity vascular injury, or documented prehospital tourniquet.

RESULTS

Among 3,444 total admissions, 165 patients met inclusion criteria. Sixty-seven patients had prehospital tourniquets (TK); 98 patients had severe extremity injuries but no prehospital tourniquet (No TK). Extremity Acute Injury Scores were the same (3.5 TK vs. 3.4 No TK) in both groups. Differences (p < 0.05) were noted in the numbers of patients with arm injuries (16.2% TK vs. 30.6% No TK), injuries requiring vascular reconstruction (29.9% TK vs. 52.5% No TK), traumatic amputations (41.8% TK vs. 26.3% No TK), and in those patients with adequate bleeding control on arrival (83% TK vs. 60% No TK). Secondary amputation rates (4 (6.0%) TK vs. 9 (9.1%) No TK); and mortality (3 (4.4%) TK vs. 4 (4.1%) No TK) did not differ. Tourniquet use was not deemed responsible for subsequent amputation in severely mangled extremities. Analysis revealed that four of seven deaths were potentially preventable with functional prehospital tourniquet placement.

CONCLUSIONS

Prehospital tourniquet use was associated with improved hemorrhage control, particularly in the worse injured (Injury Severity Score >15) subset of patients. Fifty-seven percent of the deaths might have been prevented by earlier tourniquet use. There were no early adverse outcomes related to tourniquet use.

摘要

背景

在越南战争期间,高达9%的阵亡人员死于四肢损伤导致的失血过多。对第二次世界大战期间以及以色列国防军在院前使用止血带情况的回顾性研究表明,当止血带使用时间少于6小时时,四肢出血控制情况有所改善,且肢体不良后果极少。

假设

我们假设院前使用止血带可减少四肢损伤导致的出血并挽救生命,且不会大幅增加肢体不良后果。

方法

这是一项经机构审查委员会批准的对第31战斗支援医院在伊拉克自由行动期间1年情况的回顾性研究。纳入标准为任何患有创伤性截肢、严重四肢血管损伤或有院前使用止血带记录的患者。

结果

在3444例总入院患者中,165例患者符合纳入标准。67例患者院前使用了止血带(TK组);98例患者有严重四肢损伤但院前未使用止血带(非TK组)。两组的四肢急性损伤评分相同(TK组为3.5,非TK组为3.4)。在手臂损伤患者数量(TK组为16.2%,非TK组为30.6%)、需要血管重建的损伤患者数量(TK组为29.9%,非TK组为52.5%)、创伤性截肢患者数量(TK组为41.8%,非TK组为26.3%)以及入院时出血得到充分控制的患者数量(TK组为83%,非TK组为60%)方面存在差异(p<0.05)。二次截肢率(TK组4例(6.0%),非TK组9例(9.1%))和死亡率(TK组3例(4.4%),非TK组4例(4.1%))无差异。止血带的使用未被认为是导致严重毁损肢体后续截肢的原因。分析显示,七例死亡中有四例若院前正确使用止血带可能可避免。

结论

院前使用止血带与改善出血控制相关,尤其在伤情更严重(损伤严重度评分>15)的患者亚组中。早期使用止血带可能避免57%的死亡。未发现与止血带使用相关的早期不良后果。

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