Ferrer X, Kirschbaum A, Toro J, Jadue J, Muñoz M, Espinoza A
Pontificia Universidad Católica de Chile, Facultad de Medicina, Escuela de Enfermería, Santiago, Chile.
Bol Oficina Sanit Panam. 1991 Nov;111(5):423-31.
A prospective study was conducted to estimate the current magnitude of adherence to short-course tuberculosis treatment, the degree of abandonment, the characteristics of treatment dropouts, and the causes of this abandonment. The study group was made up of tuberculosis patients over the age of 15 who received care at the Western and Southern Health Services of the Metropolitan Region of Santiago, Chile, between 1 October 1987 and 31 January 1988. The percentage abandoning treatment, calculated by the life table method, was 11.5. The profile of patients who dropped out of treatment was as follows: male, under 45 years of age, single, low level of education, no steady work, homeless, and alcoholic. In addition, an opinion survey on the variables associated with abandonment was conducted and it was concluded that the main ones were alcoholism and intolerance to tuberculosis drugs. Awareness of this profile makes it possible to take measures to prevent patients from abandoning treatment, as well as to educate and even hospitalize at the start of treatment those tuberculous patients exhibiting such a profile.
开展了一项前瞻性研究，以评估目前对短程结核病治疗的依从程度、放弃治疗的程度、治疗中断者的特征以及放弃治疗的原因。研究对象为1987年10月1日至1988年1月31日期间在智利圣地亚哥大都会区西部和南部卫生服务机构接受治疗的15岁以上结核病患者。采用寿命表法计算得出的放弃治疗百分比为11.5%。治疗中断患者的情况如下：男性，45岁以下，单身，教育程度低，无稳定工作，无家可归且酗酒。此外，还针对与放弃治疗相关的变量进行了一项意见调查，得出的结论是，主要因素是酗酒和对结核病药物不耐受。了解这一情况有助于采取措施防止患者放弃治疗，也有助于在治疗开始时对表现出此类情况的结核病患者进行教育甚至收治住院。
