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本文引用的文献

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Exocrine and endocrine pancreatic insufficiency after pancreatic surgery.胰腺手术后的外分泌和内分泌胰腺功能不全
Best Pract Res Clin Gastroenterol. 2004 Oct;18(5):947-55. doi: 10.1016/j.bpg.2004.06.028.
2
Blunt trauma of the pancreas and biliary tract: a multimodality imaging approach to diagnosis.胰腺和胆道钝性创伤:一种用于诊断的多模态成像方法
Radiographics. 2004 Sep-Oct;24(5):1381-95. doi: 10.1148/rg.245045002.
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Predictors of morbidity after traumatic pancreatic injury.创伤性胰腺损伤后发病的预测因素。
J Trauma. 2003 Nov;55(5):898-905. doi: 10.1097/01.TA.0000090755.07769.4C.
4
Long-term results of distal pancreatectomy for chronic pancreatitis in 90 patients.90例慢性胰腺炎患者行胰体尾切除术的长期结果
Ann Surg. 2002 Nov;236(5):612-8. doi: 10.1097/00000658-200211000-00011.
5
Management of major pancreatic duct injuries in children.儿童主胰管损伤的管理
J Trauma. 2001 Jun;50(6):1001-7. doi: 10.1097/00005373-200106000-00005.
6
Pancreatic trauma--injuries to the pancreas and pancreatic duct.胰腺创伤——胰腺及胰管损伤。
Eur J Surg. 2000 Jan;166(1):4-12. doi: 10.1080/110241500750009627.
7
Pancreatic trauma: Universities of Melbourne HPB Group.胰腺创伤:墨尔本大学肝脏胰腺胆管外科组
Aust N Z J Surg. 1999 May;69(5):357-62. doi: 10.1046/j.1440-1622.1999.01572.x.
8
Long-term outcome of necrotizing pancreatitis treated by necrosectomy.坏死组织切除术治疗坏死性胰腺炎的长期疗效
Br J Surg. 1998 Dec;85(12):1650-3. doi: 10.1046/j.1365-2168.1998.00950.x.
9
Diagnosis and initial management of blunt pancreatic trauma: guidelines from a multiinstitutional review.钝性胰腺创伤的诊断与初始处理:一项多机构回顾的指南
Ann Surg. 1998 Jun;227(6):861-9. doi: 10.1097/00000658-199806000-00009.
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Pancreatic trauma: a simplified management guideline.胰腺创伤:简化管理指南
J Trauma. 1997 Aug;43(2):234-9; discussion 239-41. doi: 10.1097/00005373-199708000-00005.

胰腺创伤后的结局:单机构经验

Outcomes after pancreatic trauma: experience at a single institution.

作者信息

Al-Ahmadi Khaled, Ahmed Najma

机构信息

Trauma Program and Department of Surgery, University of Toronto, Toronto, Ontario, Canada.

出版信息

Can J Surg. 2008 Apr;51(2):118-24.

PMID:18377752
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2386334/
Abstract

OBJECTIVE

Pancreatic injury following trauma is unusual, and there are few data regarding outcomes, particularly with respect to endocrine and exocrine function. The purpose of this study was to review our institutional experience in regard to this relatively infrequent injury and to determine the incidence of trauma-induced endocrine and exocrine pancreatic dysfunction as indicated by patient self-report.

METHODS

After receiving institutional research ethics approval, we identified all patients with pancreatic injuries in our trauma registry database over a 5-year period. The diagnostic, operative information, hospital course and complication rates were abstracted from medical records. Patients who could be contacted completed a telephone-administered questionnaire to assess pancreatic function.

RESULTS

We identified 25 patients who had suffered a pancreatic injury. Of these, 16 patients suffered blunt injury, and 9 suffered penetrating injury. Of the 25 patients, 13 underwent pancreatic surgery, and 6 required distal pancreatectomy. Early pancreas-specific complications occurred in 7 of 22 surviving patients (31.8%). Of the 25 patients identified, 6 could not be contacted for follow-up information. Of 19 patients contacted, 4 reported endocrine dysfunction. One of these was insulin-dependent before injury. No patient in this series reported exocrine dysfunction. The overall mortality rate in our series was 12%.

CONCLUSION

Pancreatic injuries comprised about 1% of injuries captured by our trauma registry. Outcomes were similar in patients who suffered blunt or penetrating trauma. Of these patients, 52% underwent pancreatic surgery; 16% of patients in this small series reported endocrine deficiency posttrauma.

摘要

目的

创伤后胰腺损伤并不常见,关于其预后的数据较少,尤其是在内分泌和外分泌功能方面。本研究的目的是回顾我们机构对这种相对罕见损伤的诊治经验,并通过患者自我报告确定创伤性胰腺内分泌和外分泌功能障碍的发生率。

方法

获得机构研究伦理批准后,我们在创伤登记数据库中识别了5年内所有胰腺损伤患者。从病历中提取诊断、手术信息、住院过程和并发症发生率。能够联系到的患者完成了一份电话调查问卷以评估胰腺功能。

结果

我们识别出25例胰腺损伤患者。其中,16例为钝性损伤,9例为穿透性损伤。25例患者中,13例接受了胰腺手术,6例需要行胰体尾切除术。22例存活患者中有7例(31.8%)发生了早期胰腺特异性并发症。在识别出的25例患者中,6例无法取得随访信息。在联系到的19例患者中,4例报告有内分泌功能障碍。其中1例在受伤前依赖胰岛素治疗。本系列中无患者报告有外分泌功能障碍。本系列的总死亡率为12%。

结论

胰腺损伤约占我们创伤登记所记录损伤的1%。钝性或穿透性创伤患者的预后相似。这些患者中,52%接受了胰腺手术;在这个小系列中,16%的患者创伤后报告有内分泌功能不足。