Scales Charles D, Dahm Philipp
Division of Urology, Department of Surgery, Duke University Medical Center, Durham, North Carolina, USA.
Curr Opin Urol. 2008 May;18(3):320-5. doi: 10.1097/MOU.0b013e3282fb781b.
Population-based investigations comprise a significant portion of the prostate cancer literature and contribute considerably to our knowledge of this disease. It is important to recognize, however, the inherent limitations of observational study designs. In this review, we will highlight important population-based studies in prostate cancer of high methodological quality using the framework of the recently published Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) guidelines.
Recent findings of population-based studies of prostate cancer have generated key advances in our understanding of prostate cancer outcomes and epidemiology, which are highlighted in this review. The STROBE criteria, which were developed to promote the transparent reporting of observational studies, provide an excellent framework to determine the validity of conclusions drawn from large population-based studies.
Population-based research is a powerful tool for understanding prostate cancer, but clinicians and investigators must interpret findings appropriately.
基于人群的调查在前列腺癌文献中占很大一部分，对我们了解这种疾病有很大贡献。然而，认识到观察性研究设计的固有局限性很重要。在本综述中，我们将使用最近发表的《加强流行病学观察性研究报告（STROBE）指南》框架，重点介绍前列腺癌方面方法学质量高的重要基于人群的研究。
前列腺癌基于人群研究的最新发现使我们对前列腺癌结局和流行病学的理解取得了关键进展，本综述对此进行了重点介绍。为促进观察性研究的透明报告而制定的STROBE标准，为确定从大型基于人群的研究得出的结论的有效性提供了一个极好的框架。
基于人群的研究是了解前列腺癌的有力工具，但临床医生和研究人员必须恰当地解释研究结果。
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