Wallner K
Department of Radiation Oncology, Memorial Sloan-Kettering Cancer Center.
Oncology (Williston Park). 1991 Oct;5(10):115-22; discussion 122, 125-6.
Radioactive implants have been used extensively for treatment of early stage prostate cancer. In general, their use has been associated with fewer side effects than surgery or external beam irradiation. Local control, for the most part, has been comparable to that achieved with the other modalities. Lower tumor control rates in some early series probably were related to inaccurate or inconsistent placement of radioactive pellets, since the older procedures were subject to substantial operator error. Newer transperineal techniques, guided by transrectal ultrasound or CT scanning, have provided increased accuracy of seed placement. Early results with the newer techniques are promising.
放射性植入物已被广泛用于早期前列腺癌的治疗。一般来说，与手术或外照射相比，其使用所带来的副作用较少。在很大程度上，局部控制效果与其他治疗方式相当。一些早期系列研究中较低的肿瘤控制率可能与放射性颗粒放置不准确或不一致有关，因为较旧的操作容易出现大量的操作者误差。由经直肠超声或CT扫描引导的更新的经会阴技术提高了籽源放置的准确性。新技术的早期结果很有前景。
