[塔吉克斯坦发病率下降时期急性病毒性肝炎的病因结构]

[The etiological structure of acute viral hepatitis in Tadzhikistan in a period of decreased morbidity].

作者信息

Iarasheva D M, Favorov M O, Iashina T L, Shakhgil'dian I V, Umarova A A, Sorokina S A, Kamardinov Kh K, Mavashev V I

出版信息

Vopr Virusol. 1991 Nov-Dec;36(6):454-6.

Abstract

In the period of reduced incidence of viral hepatitis in Tajikistan, January-December, 1990, 1562 patients with acute viral hepatitis (AVH) were examined in the first days of the jaundice phase (928 children under 14 years and 634 adults) in Dushanbe. Markers of hepatitis A, B, and D (HBsAg, anti-HA IgM, anti-HBc IgM, anti-delta IgM) were determined by enzyme immunoassay. Hepatitis A occurred in 25.8% of the patients with AVH, mostly children of 1-6 years, HB in 22.8%, HD co- and superinfection) in 9.2%. In 42.1% of the patients who had no HA, HB, or HD markers in the blood, non-A, non-B hepatitis (mostly hepatitis E) was diagnosed, mainly in the age groups of 30-39 years (70.7%) and 15-29 years (59.2%). Thus, in Tajikistan hepatitis E occurs not only during outbreaks of this infection but also sporadically.

摘要

在塔吉克斯坦病毒性肝炎发病率降低的时期，即1990年1月至12月，在杜尚别对1562例急性病毒性肝炎（AVH）患者在黄疸期的头几天进行了检查（928例14岁以下儿童和634例成人）。采用酶免疫分析法测定甲型、乙型和丁型肝炎标志物（HBsAg、抗-HA IgM、抗-HBc IgM、抗-δ IgM）。甲型肝炎在AVH患者中占25.8%，主要是1至6岁的儿童，乙型肝炎占22.8%，丁型肝炎合并感染和重叠感染占9.2%。在42.1%血液中无HA、HB或HD标志物的患者中，诊断为非甲非乙型肝炎（主要是戊型肝炎），主要发生在30至39岁年龄组（70.7%）和15至29岁年龄组（59.2%）。因此，在塔吉克斯坦，戊型肝炎不仅在这种感染的暴发期间发生，也呈散发性发生。