Toyoguchi S, Tsugu H, Nariai A, Kaburagi Y, Asahina Y, Ambo K, Katou K
Department of Pediatrics, Yokohama Minami-kyosai Hospital.
Acta Paediatr Jpn. 1991 Jun;33(3):394-7. doi: 10.1111/j.1442-200x.1991.tb01573.x.
A 4-month-old boy with Down syndrome and infant botulism is reported. He was admitted to our hospital with stridor and developed respiratory failure and generalized paralysis. Laboratory examination revealed botulinal toxin type A in his blood and feces. Clostridium botulinum organisms were found in the feces and in the honey which he had been fed. Anti-botulinal toxin was administered on the 10th day of illness. Artificial ventilation was given for 87 days and he survived. This is the 11th known case of infant botulism in Japan. It is possible that other cases remain undiagnosed.
报告了一名患有唐氏综合征和婴儿肉毒中毒的4个月大男孩。他因喘鸣入院，随后发展为呼吸衰竭和全身麻痹。实验室检查在其血液和粪便中发现了A型肉毒杆菌毒素。在他的粪便以及喂食的蜂蜜中发现了肉毒梭菌。在患病第10天给予了抗肉毒杆菌毒素治疗。进行了87天的人工通气，他最终存活下来。这是日本已知的第11例婴儿肉毒中毒病例。其他病例有可能仍未被诊断出来。
