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婴儿肉毒中毒。粪便中肉毒梭菌及其毒素的鉴定。

Infant botulism. Identification of Clostridium botulinum and its toxins in faeces.

作者信息

Midura T F, Arnon S S

出版信息

Lancet. 1976 Oct 30;2(7992):934-6. doi: 10.1016/s0140-6736(76)90894-1.

DOI:10.1016/s0140-6736(76)90894-1
PMID:62164
Abstract

Clostridium botulinum and its toxin were identified in the faeces of four infants, aged 6 to 13 weeks, who had symptoms consistent with botulism. Two cases had type-A toxin and two cases had type-B toxin present in their faeces. No toxin was detectable in sera C. botulinum and toxin could be recovered from faeces more than 8 weeks after admission to hospital. All four cases occurred within a 6-month period. The source of the toxin in these infants may have been in-vivo production from ingested organisms.

摘要

在4名年龄为6至13周、有肉毒中毒相关症状的婴儿粪便中发现了肉毒梭菌及其毒素。2例粪便中存在A型毒素,2例存在B型毒素。血清中未检测到肉毒梭菌毒素,且在入院8周多后仍可从粪便中分离出毒素。所有4例均发生在6个月内。这些婴儿体内毒素的来源可能是摄入的生物体在体内产生的。

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