由一种商业食品引发的B型肉毒中毒疫情。西弗吉尼亚州和宾夕法尼亚州，1973年。

Type B botulism outbreak caused by a commercial food product. West Virginia and Pennsylvania, 1973.

作者信息

Barker W H, Weissmann J B, Dowell V R, Gutmann L, Kautter D A

出版信息

JAMA. 1977 Jan 31;237(5):456-9.

Abstract

In the week of May 7, 1973, seven persons contracted botulism after eating together. The most common symptoms were vomiting, constipation, dry mouth, dysphagia, and dysphonia. All were treated with trivalent botulinal antitoxin, and none died. Serum specimens obtained from all seven patients were negative for botulinal toxin, but stool specimens from three patients were positive for type B toxin. Electromyographic studies performed on five patients documented the neurophysiologic abnormalities of botulism. Commercially canned peppers in oil were implicated epidemiologically, and type B toxin was identified in leftover peppers. The processor voluntarily recalled the pepper product, and no further cases were reported.

摘要

1973年5月7日那周，七人聚餐后感染肉毒杆菌中毒。最常见的症状是呕吐、便秘、口干、吞咽困难和发音困难。所有患者均接受了三价肉毒杆菌抗毒素治疗，无一死亡。从所有七名患者身上采集的血清样本肉毒杆菌毒素检测呈阴性，但三名患者的粪便样本B型毒素检测呈阳性。对五名患者进行的肌电图研究记录了肉毒杆菌中毒的神经生理异常。从流行病学角度看，涉事食品为市售罐装油浸辣椒，在剩余辣椒中检测出了B型毒素。生产商主动召回了辣椒产品，之后未再报告新的病例。