Petković Marija, Krstulja Mira, Radic Jelena, Zamolo Gordana, Muhvić Damir, Lovasic Ingrid, Kujundzic Milodar, Franko Artur
Department of Radiotherapy and Oncology, Clinical Hospital Centre Rijeka, Rijeka, Croatia.
Int J Surg Pathol. 2008 Jul;16(3):337-40. doi: 10.1177/1066896907312670. Epub 2008 Apr 2.
A case of rare tumor, Merkel cell carcinoma, located in the ear canal of a 25-year-old woman is presented. A polypoid tumor mass was extirpated, and tympanoplasty was done at the first operation, whereas at the second operation, all the bones of the ear canal were removed. Epitympanum and cavum were filled with tumor, and the tumor mass was removed in toto. The histopathology and immunohistochemical staining characteristics of tumor confirmed the presence of Merkel cell tumor. Postoperatively, radiation therapy to the tumor bed was completed. There was no clinical or radiographic evidence of recurrence or metastasis of Merkel cell tumor for 3 years.
本文报道了一例罕见肿瘤——默克尔细胞癌,发生于一名25岁女性的耳道。首次手术切除了息肉样肿瘤块,并进行了鼓室成形术,而第二次手术则切除了所有耳道骨质。上鼓室和鼓室腔充满肿瘤,遂将肿瘤块整块切除。肿瘤的组织病理学和免疫组化染色特征证实为默克尔细胞瘤。术后对瘤床完成了放射治疗。3年来无默克尔细胞瘤复发或转移的临床或影像学证据。