Verschoore M, Poncet M, Schaefer H, Revuz J, De Prost Y, Guillaume J C, Ortonne J P, Czernielewski J
Centre de Pharmacologie Clinique Appliquée à la Dermatologie, (C.P.C.A.D.), Hôpital Pasteur, Nice.
Therapie. 1991 May-Jun;46(3):189-91.
Acne is a frequent dermatologic disease of the teenagers. Methodology of antiacne preparations clinical trials has evolved recently, leading to better comprehension of acne treatment on acne lesions. The main rules for good clinical evaluation of acne treatments are: an objective counting of each individual lesions on a defined area (face, back), a global acne assessment, a therapy duration from 1 to 3 months or more, a skin safety evaluation for erythema, desquamation, dryness, itching, burning and oiliness with a 0 to 3 scoring system.
痤疮是青少年常见的皮肤病。近年来，抗痤疮制剂的临床试验方法不断发展，有助于更好地理解痤疮治疗对痤疮皮损的作用。痤疮治疗良好临床评估的主要规则包括：在规定区域（面部、背部）对每个个体皮损进行客观计数、进行整体痤疮评估、治疗持续时间为1至3个月或更长、采用0至3评分系统对红斑、脱屑、干燥、瘙痒、灼痛和油腻等皮肤安全性进行评估。
