Volla Trude Tangen, Kopperud Gry Stine
Pfizer AS, Postboks 3, 1324 Lysaker.
Tidsskr Nor Laegeforen. 2008 Apr 3;128(7):826-8.
Treatment guidelines for chronic obstructive pulmonary disease (COPD) recommend that disease severity should be decisive for the choice of drug.
Medical records for patients with COPD were reviewed and an overview was made of the different drugs used for maintenance treatment. We examined the correspondence between drug classes used and guideline recommendations.
Glucocorticosteroids and long-acting bronchodilators are used more frequently for maintenance treatment than anticholinergic drugs and short-acting bronchodilators. The severity of COPD does not influence the prescription of glucocorticosteroides and long-acting bronchodilators.
The physician's first choice of drug seems to continue as maintenance treatment. The results suggest that glucocorticosteroids are used more frequently than recommended by the COPD treatment guidelines.
慢性阻塞性肺疾病(COPD)治疗指南建议,疾病严重程度应作为药物选择的决定性因素。
回顾了COPD患者的病历,并对用于维持治疗的不同药物进行了概述。我们检查了所用药物类别与指南建议之间的对应关系。
与抗胆碱能药物和短效支气管扩张剂相比,糖皮质激素和长效支气管扩张剂在维持治疗中使用更为频繁。COPD的严重程度不影响糖皮质激素和长效支气管扩张剂的处方。
医生首选的药物似乎继续用于维持治疗。结果表明,糖皮质激素的使用频率高于COPD治疗指南的推荐。