Department of General Practice, Institute of Health and Society, University of Oslo, 0318 Oslo, Norway.
Eur J Gen Pract. 2013 Jun;19(2):106-10. doi: 10.3109/13814788.2013.766713. Epub 2013 Apr 5.
Inhaled glucocorticosteroids (ICS) are first-line anti-inflammatory treatment in asthma, but not in chronic obstructive pulmonary disease (COPD). To restrict ICS use in COPD to cases of severe disease, new terms for reimbursement of drug costs were introduced in Norway in 2006, requiring a diagnosis of COPD to be verified by spirometry.
To describe how GPs' diagnoses and treatment of patients who used ICS before 2006 changed after a reassessment of the patients that included spirometry.
From the shared electronic patient record system in one group practice, patients ≥ 50 years prescribed ICS (including in combination with long-acting beta2-agonists) during the previous year were identified and invited to a tailored consultation including spirometry to assure the quality of diagnosis and treatment. GPs' diagnoses and ICS prescribing patterns after this reassessment were recorded, retrospectively.
Of 164 patients identified, 112 were included. Post-bronchodilator spirometry showed airflow limitation indicating COPD in 55 patients. Of the 57 remaining patients, five had a positive reversibility test. The number of patients diagnosed with asthma increased (from 25 to 62) after the reassessment. A diagnosis of COPD was also more frequently used, whereas fewer patients had other pulmonary diagnoses. ICS was discontinued in 31 patients; 20 with mild to moderate COPD and 11 with normal spirometry.
Altered reimbursement terms for ICS changed GPs' diagnostic practice in a way that made the diagnoses better fit with the treatment given, but over-diagnosis of asthma could not be excluded. Spirometry was useful for identifying ICS overuse.
吸入性糖皮质激素(ICS)是哮喘的一线抗炎治疗药物,但不是慢性阻塞性肺疾病(COPD)的一线治疗药物。为了将 ICS 在 COPD 中的使用限制在严重疾病的情况下,挪威于 2006 年引入了新的药物费用报销条款,要求通过肺活量测定法验证 COPD 的诊断。
描述在重新评估包括肺活量测定法在内的患者后,全科医生对使用 ICS 前的患者的诊断和治疗方法的变化。
从一个小组实践的共享电子病历系统中,确定了前一年开具 ICS(包括与长效β2-激动剂联合使用)的≥50 岁患者,并邀请他们进行量身定制的咨询,包括肺活量测定法,以确保诊断和治疗的质量。记录了重新评估后全科医生的诊断和 ICS 处方模式。
在确定的 164 名患者中,有 112 名患者被纳入研究。支气管扩张剂后肺活量测定法显示,55 名患者存在气流受限,提示 COPD。在其余 57 名患者中,有 5 名患者的可逆性试验阳性。经过重新评估后,被诊断为哮喘的患者数量增加(从 25 例增加到 62 例)。更频繁地使用 COPD 诊断,而其他肺部诊断则减少。31 名患者停用了 ICS;20 名患者患有轻度至中度 COPD,11 名患者的肺活量测定法正常。
改变 ICS 的报销条款改变了全科医生的诊断实践,使诊断更符合所给予的治疗,但不能排除过度诊断哮喘。肺活量测定法可用于识别 ICS 的过度使用。