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医院招募的和基于人群的 COPD 患者的指南依从性。

Guideline adherence in hospital recruited and population based COPD patients.

机构信息

Department of Thoracic Medicine, Haukeland University Hospital, Bergen, Norway.

Department of Clinical Science, University of Bergen, N-5021, Bergen, Norway.

出版信息

BMC Pulm Med. 2018 Dec 20;18(1):195. doi: 10.1186/s12890-018-0756-8.

Abstract

BACKGROUND

Evidence from several studies show poor guideline adherence to COPD treatment, but no such study has been undertaken in Norway. The objectives of this study, was to estimate and compare the guideline adherence to COPD treatment in general population-based and hospital-recruited COPD patients, and find possible predictors of guideline adherence.

METHODS

From the prospective, observational EconCOPD-study, we analysed guideline adherence for 90 population-based COPD cases compared to 245 hospital-recruited COPD patients. Overall guideline adherence was defined as correct pharmacological treatment, and influenza vaccination the preceding year, and having received smoking cessation advice. Multivariate logistic regression analysis was performed with the dichotomous outcome overall guideline adherence adjusting for relevant variables.

RESULTS

The overall guideline adherence for population-based COPD cases was 6.7%, significantly lower than the 29.8% overall guideline-adherence amongst hospital-recruited COPD patients. Adherence to pharmacological treatment guidelines was 10.0 and 35.5%, for the two recruitment sources, respectively. GOLD-stage 3 to 4 was associated with significantly better guideline adherence compared to GOLD-stage 2 (OR (95% CI) 18.9 (8.37,42.7)). The unadjusted difference between the two recruitment sources was completely explained by degree of airflow obstruction.

CONCLUSION

Overall guideline adherence was very low for both recruitment sources. We call for increased attention from authorities and healthcare personnel to improve the quality of care given to this patient group.

摘要

背景

多项研究的证据表明,COPD 治疗的指南遵循率较差,但挪威尚未开展此类研究。本研究的目的是评估和比较基于人群的 COPD 患者和医院招募的 COPD 患者对 COPD 治疗的指南遵循情况,并找出可能的指南遵循预测因素。

方法

我们从前瞻性、观察性的 EconCOPD 研究中分析了 90 例基于人群的 COPD 病例和 245 例医院招募的 COPD 患者的指南遵循情况。总体指南遵循定义为正确的药物治疗、前一年接种流感疫苗以及接受戒烟建议。使用二项逻辑回归分析,以总体指南遵循作为二项结果,调整了相关变量。

结果

基于人群的 COPD 病例的总体指南遵循率为 6.7%,明显低于医院招募的 COPD 患者的 29.8%。药物治疗指南的遵循率分别为 10.0%和 35.5%。与 GOLD 分期 2 相比,GOLD 分期 3 至 4 与更好的指南遵循显著相关(OR(95%CI)18.9(8.37,42.7))。两个招募来源之间的未调整差异完全由气流阻塞程度解释。

结论

两个招募来源的总体指南遵循率都非常低。我们呼吁当局和医疗保健人员更加关注,以提高对这一患者群体的护理质量。

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