Brotanek Jane M, Gosz Jacqueline, Weitzman Michael, Flores Glenn
Department of Pediatrics, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75390-9063, USA.
Arch Pediatr Adolesc Med. 2008 Apr;162(4):374-81. doi: 10.1001/archpedi.162.4.374.
To examine secular trends in iron deficiency among US children 1 to 3 years old.
Secular trend analyses of the National Health and Nutrition Examination Survey II-IV.
Large-scale national survey conducted by the National Center for Health Statistics from 1976 to 2002.
US children 1 to 3 years old. Outcome Measure Prevalence of iron deficiency.
Between 1976 and 2002, there was no change in iron deficiency prevalence in US toddlers. Iron deficiency prevalence remained unchanged in Hispanic and white toddlers but decreased among black toddlers. Across all 3 survey waves, racial/ethnic disparities in iron deficiency persisted between Hispanic and white toddlers, with a disparity ratio of at least 2. Iron deficiency prevalence remained high (20%-24%) in overweight toddlers, significantly higher than in those at risk for overweight (11%) and in normal weight or underweight toddlers (8%). Iron deficiency prevalence decreased from 22% to 9% in toddlers in poor households but remained unchanged in toddlers in nonpoor households (7%). In multivariable analyses, Hispanic, younger, and overweight toddlers had higher odds of iron deficiency.
Despite the decline in iron deficiency prevalence among 1-year-old, black, and poor children, iron deficiency prevalence in US toddlers overall has not changed in the last 26 years and remains elevated in certain high-risk groups: Hispanic, younger, and overweight toddlers. Efforts to reduce the prevalence of iron deficiency in infancy and early childhood are urgently needed and should target high-risk groups.
研究美国1至3岁儿童缺铁情况的长期趋势。
对国家健康与营养检查调查II - IV进行长期趋势分析。
1976年至2002年由国家卫生统计中心开展的大规模全国性调查。
美国1至3岁儿童。结局指标为缺铁患病率。
1976年至2002年期间,美国学步儿童的缺铁患病率没有变化。西班牙裔和白人学步儿童的缺铁患病率保持不变,但黑人学步儿童的患病率有所下降。在所有3次调查中,西班牙裔和白人学步儿童在缺铁方面的种族/族裔差异持续存在,差异比至少为2。超重学步儿童的缺铁患病率仍然很高(20% - 24%),显著高于超重风险儿童(11%)以及正常体重或体重不足的学步儿童(8%)。贫困家庭学步儿童的缺铁患病率从22%降至9%,但非贫困家庭学步儿童的患病率保持不变(7%)。在多变量分析中,西班牙裔、年龄较小和超重的学步儿童缺铁的几率更高。
尽管1岁、黑人及贫困儿童的缺铁患病率有所下降,但在过去26年中,美国学步儿童的总体缺铁患病率并未改变,在某些高危群体中仍然居高不下:西班牙裔、年龄较小和超重的学步儿童。迫切需要努力降低婴儿期和幼儿期的缺铁患病率,且应针对高危群体。