Gelbrich Thomas, Bingham Ann L, Threlfall Terence L, Hursthouse Michael B
University of Southampton, School of Chemistry, Highfield, Southampton SO17 1BJ, England.
Acta Crystallogr C. 2008 Apr;64(Pt 4):o205-7. doi: 10.1107/S0108270108005696. Epub 2008 Mar 8.
The delta polymorph of sulfanilamide (or 4-aminobenzenesulfonamide), C(6)H(8)N(2)O(2)S, displays an overall three-dimensional hydrogen-bonded network that is dominated by a two-dimensional substructure with R(2)(2)(8) rings; these result from dimeric N-H...O interactions between adjacent sulfonamide groups. This study shows how the polymorphism of sulfanilamide is linked to its versatile hydrogen-bonding capabilities.
磺胺(或4-氨基苯磺酰胺)C₆H₈N₂O₂S的δ多晶型物呈现出一个整体的三维氢键网络,该网络由具有R₂²(8)环的二维子结构主导;这些是由相邻磺酰胺基团之间的二聚体N-H...O相互作用产生的。这项研究展示了磺胺的多晶型现象是如何与其多样的氢键形成能力相关联的。