Hukki Jyri, Saarinen Pia, Kangasniemi Marko
Department of Plastic Surgery, Cleft Palate and Craniofacial Centre Helsinki, Finland.
Front Oral Biol. 2008;12:79-90. doi: 10.1159/000115033.
Craniosynostosis, premature suture fusion, is one of the most common craniofacial anomalies affecting approximately 1 in 2,500 live births. Craniosynostosis is most commonly an isolated (nonsyndromic) condition with the sagittal suture being the most commonly affected suture. In this review we describe the range of isolated synostoses and show how these can lead to a variety of different morphological and functional abnormalities.
颅缝早闭,即颅骨缝过早融合,是最常见的颅面畸形之一,每2500例活产中约有1例受影响。颅缝早闭最常见的是一种孤立性(非综合征性)疾病,矢状缝是最常受累的颅骨缝。在本综述中,我们描述了孤立性颅缝早闭的范围,并展示了这些如何导致各种不同的形态和功能异常。