Kazi R, Prasad V, Venkitaraman R, Nutting C M, Clarke P, Rhys-Evans P, Harrington K J
Head and Neck Unit, Royal Marsden Hospital, London, UK.
ORL J Otorhinolaryngol Relat Spec. 2008;70(3):151-5. doi: 10.1159/000124287. Epub 2008 Apr 8.
To determine the effects of a partial/total glossectomy on the swallow-related quality of life (QOL).
Cross-sectional, single-centre cohort study.
Thirty-one patients who underwent partial/total glossectomy at our centre participated in the study. Main outcome was measured using the MD Andersen Dysphagia Inventory (MDADI) questionnaire.
Responses were received from 24 males and 7 females (response rate of 77.5%) with a median age of 50 years (range: 28-72). Median follow-up in patients was 33 months (range 4-210). The mean MDADI total score in our series of patients was 71.7 (SD 18.8). Mean MDADI global score was 64.5 (SD 29.1), mean Emotional score was 71.9 (SD 19.1), mean Functional score was 73.7 (SD 19.1) and mean Physical score was 69.3 (SD 21.7). Statistically significant differences were seen between the global, emotional and physical scores of patients who had received radiotherapy (Mann-Whitney, p < 0.05) and tracheostomy (functional score, Mann-Whitney, p = 0.038).
The presence of tracheostomy tube and previous radiotherapy affects swallowing outcome in patients who have had surgery for squamous cell carcinoma of the tongue.
确定部分/全舌切除术对吞咽相关生活质量(QOL)的影响。
横断面单中心队列研究。
在我们中心接受部分/全舌切除术的31例患者参与了本研究。主要结局采用MD安德森吞咽障碍量表(MDADI)问卷进行测量。
共收到24例男性和7例女性的回复(回复率为77.5%),中位年龄为50岁(范围:28 - 72岁)。患者的中位随访时间为33个月(范围4 - 210个月)。我们这组患者的MDADI总分平均为71.7(标准差18.8)。MDADI总体评分平均为64.5(标准差29.1),情感评分平均为71.9(标准差19.1),功能评分平均为73.7(标准差19.1),身体评分平均为69.3(标准差21.7)。接受过放疗的患者在总体、情感和身体评分方面(曼 - 惠特尼检验,p < 0.05)以及接受过气管切开术的患者在功能评分方面(曼 - 惠特尼检验,p = 0.038)存在统计学显著差异。
气管切开管的存在和既往放疗会影响舌鳞状细胞癌手术患者的吞咽结局。