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口腔癌治疗患者生活质量的科学证据水平。

Levels of scientific evidence of the quality of life in patients treated for oral cancer.

机构信息

School of Dentistry, University of Granada, Granada, Spain.

出版信息

Med Oral Patol Oral Cir Bucal. 2013 Jul 1;18(4):e578-84. doi: 10.4317/medoral.19052.

DOI:10.4317/medoral.19052
PMID:23722141
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3731084/
Abstract

Treatments used in cancer of the oral cavity have great impact on the physical, psychological and functional state of patients. There has been increasingly interest in evaluating the health-related quality of life using questionnaires among patients treated with oral cancer. Up to our knowledge no review on this theme has incorporated the level of evidence of the single identified studies. The objective of the present study is to determinate results and conclusions about the health-related quality of life of these patients, in view of scientific evidence. In general, the diversity of designs, level of evidence and questionnaires used for their assessment does not affect results, which indicate a decline in the health related quality of life after treatment. This decline is greater when the tumor is large in size, and when radiotherapy is used, though the situation is seen to improve over the span of a year. Questionnaires on health-related quality of life provide concrete information regarding the impact of cancer treatment on patients.

摘要

口腔癌的治疗方法对患者的身体、心理和功能状态有很大影响。越来越多的人关注使用问卷调查评估口腔癌患者的健康相关生活质量。据我们所知,尚无关于该主题的综述纳入了单一研究的证据水平。本研究的目的是根据科学证据确定这些患者的健康相关生活质量的结果和结论。一般来说,设计、证据水平和用于评估的问卷的多样性并不影响结果,这些结果表明治疗后健康相关生活质量下降。当肿瘤较大且使用放射治疗时,下降更为明显,但随着时间的推移,情况会有所改善。健康相关生活质量问卷提供了关于癌症治疗对患者影响的具体信息。

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本文引用的文献

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Two-year quality of life after free flap reconstruction in tumor-site discrepancy among Taiwanese with moderately advanced oral squamous cell carcinoma.台湾中晚期口腔鳞状细胞癌患者游离皮瓣重建后肿瘤部位差异的两年生活质量。
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