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减压性颅骨切除术

Decompressive Craniectomy.

作者信息

Schirmer Clemens M, Ackil Albert A, Malek Adel M

机构信息

Cerebrovascular and Endovascular Division, Department of Neurosurgery, Tufts Medical Center, Tufts University School of Medicine, 800 Washington Street #178, Boston, MA 02111, USA.

出版信息

Neurocrit Care. 2008;8(3):456-70. doi: 10.1007/s12028-008-9082-y.

Abstract

Decompressive Craniectomy (DC) is used to treat elevated intracranial pressure that is unresponsive to conventional treatment modalities. The underlying cause of intracranial hypertension may vary and consequently there is a broad range of literature on the uses of this procedure. Traumatic brain injury (TBI), middle cerebral artery (MCA) infarction, and aneurysmal subarachnoid hemorrhage (SAH) are three conditions for which DC has been predominantly used in the past. Despite an increasing number of reports supportive of DC, the controversy over the suitability of the procedure and criteria for patient selection remains unresolved. Although the majority of published studies is retrospective, the recent publication of several randomized prospective studies prompts a reevaluation of the utility of DC. We review the literature concerning the use of DC in TBI, MCA infarction, and SAH and address the evidence regarding common questions pertaining to the timing of and laterality of the procedure. We conclude that at the time of this review, there still remains insufficient data to support the routine use of DC in TBI, stroke or SAH. There is evidence that early and aggressive use of DC in good-grade patients may improve outcome, but the notion that DC is indicated in these patients is contentious. At this point, the indication for DC should be individualized and its potential implications on long-term outcomes should be comprehensively discussed with the caregivers.

摘要

减压性颅骨切除术(DC)用于治疗对传统治疗方式无反应的颅内压升高。颅内高压的潜在病因可能各不相同,因此关于该手术用途的文献范围广泛。创伤性脑损伤(TBI)、大脑中动脉(MCA)梗死和动脉瘤性蛛网膜下腔出血(SAH)是过去DC主要应用的三种情况。尽管支持DC的报告越来越多,但关于该手术的适用性和患者选择标准的争议仍未解决。虽然大多数已发表的研究是回顾性的,但最近几项随机前瞻性研究的发表促使人们重新评估DC的效用。我们回顾了有关DC在TBI、MCA梗死和SAH中应用的文献,并讨论了与该手术时机和手术侧别相关的常见问题的证据。我们得出结论,在本次综述时,仍然没有足够的数据支持在TBI、中风或SAH中常规使用DC。有证据表明,在病情较好的患者中早期积极使用DC可能会改善预后,但在这些患者中使用DC的观点存在争议。此时,DC的适应症应个体化,并应与护理人员全面讨论其对长期预后的潜在影响。

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