Shinfeld Amihay, Raanani Ehud
Department of Cardiac and Thoracic Surgery, The Chaim Sheba Medical Center, Tel Hashomer, Israel.
Langenbecks Arch Surg. 2009 Mar;394(2):345-8. doi: 10.1007/s00423-008-0305-7. Epub 2008 Apr 8.
Late ascending aortic dissection after coronary artery bypass grafting (CABG) is an uncommon phenomenon, and treatment presents a complex clinical dilemma.
Between 1995 and 2005, eight patients were diagnosed with post-CABG late acute aortic dissection. Mean age was 61.7 (range 52-76), and mean period between CABG and late acute aortic dissection was 45.3 months (range 5 to 122 months). Three patients underwent surgical replacement of the ascending aorta. One patient died after surgery, and the other two had an uneventful recovery, with a successful mean 6.5-year follow-up. Five patients were treated conservatively, with a mean follow-up of 81.2 months (range 50-112 months).
Periodic computed tomography (CT) scans showed minor or no change in aortic diameter and satisfactory general condition. Late acute aortic dissection after CABG is rare. Only a few reports have been published, and no standard treatment guidelines exist.
We assume that postoperative pericardial scarring and adhesions provide some protection against progression of the dissection and therefore suggest that preferred treatment in non-stable patients should be surgical. In stable patients, close follow-up and blood pressure control are beneficial. Late ascending aortic dissection after CABG is rare, and treatment presents a clinical dilemma. We treated eight patients with post-CABG late acute aortic dissection. Three underwent surgical replacement of the ascending aorta. One died after surgery, and the other two had an uneventful recovery. Five patients were treated conservatively. No standard treatment guidelines exist for late acute aortic dissection after CABG. We assume that postoperative pericardial scarring and adhesions provide some protection against progression of the dissection, and suggest that preferred treatment in non-stable patients should be surgical. In stable patients, close follow-up and blood pressure control are beneficial.
冠状动脉旁路移植术(CABG)后晚期升主动脉夹层是一种罕见现象,其治疗面临复杂的临床困境。
1995年至2005年间,8例患者被诊断为CABG术后晚期急性主动脉夹层。平均年龄为61.7岁(范围52 - 76岁),CABG与晚期急性主动脉夹层之间的平均间隔时间为45.3个月(范围5至122个月)。3例患者接受了升主动脉手术置换。1例患者术后死亡,另外2例恢复顺利,平均随访6.5年成功。5例患者接受保守治疗,平均随访81.2个月(范围50 - 112个月)。
定期计算机断层扫描(CT)显示主动脉直径变化轻微或无变化,总体状况良好。CABG术后晚期急性主动脉夹层罕见。仅有少数报告发表,且不存在标准治疗指南。
我们认为术后心包瘢痕形成和粘连对夹层进展有一定保护作用,因此建议对不稳定患者首选手术治疗。对于稳定患者,密切随访和血压控制有益。CABG术后晚期升主动脉夹层罕见,治疗面临临床困境。我们治疗了8例CABG术后晚期急性主动脉夹层患者。3例接受了升主动脉手术置换。1例术后死亡,另外2例恢复顺利。5例患者接受保守治疗。CABG术后晚期急性主动脉夹层不存在标准治疗指南。我们认为术后心包瘢痕形成和粘连对夹层进展有一定保护作用,建议对不稳定患者首选手术治疗。对于稳定患者,密切随访和血压控制有益。