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[1岁婴儿的经胎盘麻疹免疫力]

[Transplacental measles immunity in infants in the 1st year of life].

作者信息

Bystriakova L V, Zaĭtseva R V, Kolobova L V, Pushkareva E A, Smorodinova I P

出版信息

Zh Mikrobiol Epidemiol Immunobiol. 1991 Oct(10):50-2.

PMID:1839342
Abstract

A total of 187 parturients (66 with a history of measles and 121 immunized with live measles vaccine, or LMV, in childhood) and their 187 newborn infants, as well as 195 children aged up to 1 year, were examined. Antimeasles antibodies in blood sera were detected in the hemagglutination inhibition test. In all mothers with a history of measles and in their newborn infants antimeasles antibodies in different titers were detected. In mothers, formerly immunized with LMV, antimeasles antibodies were absent in 5.8% and in their newborn infants, in 6.6% of the examinees. Among children aged up to 1 year, born of formerly immunized mothers, more rapid disappearance of passive antimeasles immunity was observed. In cases of contact with measles, the serological examinations of all children born of mothers immunized with LMV should be carried out in order to protect seronegative children by passive or active immunization.

摘要

对187名产妇(66名有麻疹病史,121名在儿童期接种过麻疹活疫苗)及其187名新生儿,以及195名1岁以下儿童进行了检查。采用血凝抑制试验检测血清中的抗麻疹抗体。在所有有麻疹病史的母亲及其新生儿中均检测到不同滴度的抗麻疹抗体。在曾接种过麻疹活疫苗的母亲中,5.8%的母亲及6.6%的受检新生儿未检测到抗麻疹抗体。在曾接种过疫苗的母亲所生的1岁以下儿童中,观察到被动抗麻疹免疫力消失得更快。在接触麻疹的情况下,应对所有曾接种过麻疹活疫苗的母亲所生儿童进行血清学检查,以便通过被动或主动免疫保护血清阴性儿童。

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