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脊髓损伤患者的人工尿道括约肌:改良技术描述及临床结果

The artificial urinary sphincter in patients with spinal cord lesion: description of a modified technique and clinical results.

作者信息

Bersch Ulf, Göcking Konrad, Pannek Jürgen

机构信息

Department of Neuro-Urology, Swiss Paraplegic Center, Nottwil, Switzerland.

出版信息

Eur Urol. 2009 Mar;55(3):687-93. doi: 10.1016/j.eururo.2008.03.046. Epub 2008 Mar 31.

Abstract

BACKGROUND

The artificial sphincter is the method of choice in patients with stress urinary incontinence due to neurogenic bladder dysfunction. However, long-term studies reveal a high revision rate.

OBJECTIVE

To determine the success and revision rates of a modified implant.

DESIGN, SETTING, AND PARTICIPANTS: In a retrospective analysis, the results of 51 consecutive patients presenting at a private paraplegic center with neurogenic bladder dysfunction (meningomyelocele: n=8; spinal cord injury: n=37; others: n=6) who underwent implantation of an artificial sphincter at the bladder neck using a port instead of a pump were evaluated.

MEASUREMENTS

Subjective and objective cure rates were assessed by video-urodynamics and a standardized interview.

RESULTS AND LIMITATIONS

After a mean follow up of 95.9 mo, 70.6% of the patients were objectively and subjectively cured; 90.2% were completely continent in everyday life. Mean bladder capacity (465 ml) and compliance (41.7 ml/cm H(2)O) were normal. Sixteen patients underwent 18 revisions (35.3%). One implant had to be permanently removed. This is a single-centre study; thus, the results have to be confirmed.

CONCLUSIONS

With a long follow up of 8 yr, the modification presented by our group proved to be highly successful, reliable, safe, and even cost-effective. Therefore, it seems to be a valuable tool for the treatment of this group of patients.

摘要

背景

人工括约肌是治疗神经源性膀胱功能障碍所致压力性尿失禁患者的首选方法。然而,长期研究显示其翻修率较高。

目的

确定一种改良植入物的成功率和翻修率。

设计、场所和参与者:在一项回顾性分析中,对51例连续就诊于一家私立截瘫中心、患有神经源性膀胱功能障碍(脊髓脊膜膨出:n = 8;脊髓损伤:n = 37;其他:n = 6)的患者进行了评估,这些患者在膀胱颈植入了使用端口而非泵的人工括约肌。

测量指标

通过影像尿动力学和标准化访谈评估主观和客观治愈率。

结果和局限性

平均随访95.9个月后,70.6%的患者在主观和客观上均治愈;90.2%的患者在日常生活中完全控尿。平均膀胱容量(465 ml)和顺应性(41.7 ml/cm H₂O)正常。16例患者进行了18次翻修(35.3%)。1例植入物不得不永久取出。这是一项单中心研究;因此,结果有待证实。

结论

经过8年的长期随访,我们团队提出的改良方法被证明非常成功、可靠、安全且具有成本效益。因此,它似乎是治疗这类患者的一种有价值的工具。

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