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用于神经源性尿失禁的人工尿道括约肌:一项叙述性综述。

Artificial urinary sphincter for neurogenic urinary incontinence: a narrative review.

作者信息

Findlay Bridget L, Elliott Daniel S

机构信息

Department of Urology, Mayo Clinic, Rochester, MN, USA.

出版信息

Transl Androl Urol. 2024 Aug 31;13(8):1738-1743. doi: 10.21037/tau-22-794. Epub 2023 Jun 19.

Abstract

BACKGROUND AND OBJECTIVE

The artificial urinary sphincter (AUS) is most known for its use in the treatment of moderate to severe post-prostatectomy stress urinary incontinence. However, another lesser-known indication includes stress incontinence related to intrinsic sphincter deficiency (ISD) in the neurogenic bladder population. The purpose of this review is to discuss specific technical considerations related to device implantation in this population, efficacy, durability, and complications.

METHODS

We performed a non-systematic literature review using the PubMed Database to identify articles specifically related to treatment of neurogenic urinary incontinence using an artificial urinary sphincter.

KEY CONTENT AND FINDINGS

More proximal placement of the cuff at the bladder neck is preferred in the neurogenic population due to higher rates of erosion and complications related to frequent clean intermittent catheterization or cystoscopic procedures when placed along the bulbar urethra. Robotic-assisted laparoscopic cuff placement has emerged as a safe and effective alternative to open surgery in select patients. Although continence rates are highly variable due the subjectivity of the term, functional continence (≤1 pad, ± nighttime incontinence) is reported to be between 75-90%. The need for secondary surgery for explanation with or without revision/replacement is higher in neurogenic patients compared to non-neurogenic patients.

CONCLUSIONS

Neurogenic urinary incontinence is a complex condition due to the interplay of urethral resistance and bladder function/compliance. While there are a variety of strategies to treat neurogenic incontinence, high quality data from direct comparisons are lacking. Although AUS comes with a high revision rate, functional outcomes for continence with bladder neck placement are promising in this population.

摘要

背景与目的

人工尿道括约肌(AUS)最为人所知的用途是治疗前列腺切除术后的中重度压力性尿失禁。然而,另一个鲜为人知的适应症是神经源性膀胱患者中与固有括约肌缺陷(ISD)相关的压力性尿失禁。本综述的目的是讨论与该人群中装置植入相关的具体技术考量、疗效、耐用性及并发症。

方法

我们使用PubMed数据库进行了非系统性文献综述,以识别与使用人工尿道括约肌治疗神经源性尿失禁具体相关的文章。

关键内容与发现

在神经源性患者中,由于沿球部尿道放置时,因频繁清洁间歇性导尿或膀胱镜检查导致的侵蚀和并发症发生率较高,因此更倾向于将袖带置于膀胱颈更近端的位置。在部分患者中,机器人辅助腹腔镜袖带置入已成为开放手术的一种安全有效的替代方法。尽管由于“控尿”这一术语的主观性,控尿率差异很大,但据报道,功能性控尿(≤1片尿垫,±夜间尿失禁)率在75%至90%之间。与非神经源性患者相比,神经源性患者因解释原因而进行二次手术(无论是否进行翻修/更换)的需求更高。

结论

由于尿道阻力与膀胱功能/顺应性之间的相互作用,神经源性尿失禁是一种复杂的病症。虽然有多种治疗神经源性尿失禁的策略,但缺乏直接比较的高质量数据。尽管AUS的翻修率较高,但在该人群中,膀胱颈放置后的控尿功能结果很有前景。

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