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[居住在苏联欧洲北部地区的甲状腺疾病患者的脂质代谢特征]

[The lipid metabolic characteristics of patients with thyroid pathology living in the European north of the USSR].

作者信息

Shatsova E N, Kononov E I, Suslonova G A, Romanova T B

出版信息

Ter Arkh. 1991;63(10):54-6.

PMID:1839583
Abstract

The blood content of total lipids, triglycerides, total cholesterol, alpha- and beta-lipoprotein cholesterol was measured in 79 patients with diffuse toxic goiter during treatment, in 25 patients with hypothyroidism, in 33 with thyroid hyperplasia, and in 54 healthy women aged 35-60 years from the group of native population of the European North. In all the forms of thyroid dysfunction, the patients manifested dyslipoproteinemia in the form of hypercholesterolemia with an increase of the concentration of beta-cholesterol, hypertriglyceridemia, and with a rise of the cholesterol atherogenic index to 4.0 and over. The signs of dyslipoproteinemia were marked to the greatest degree in thyrotoxicosis, at the stages of euthyroidism attainment or disease remissions.

摘要

对79例弥漫性毒性甲状腺肿患者治疗期间的总脂质、甘油三酯、总胆固醇、α和β脂蛋白胆固醇的血液含量进行了测定,还测定了25例甲状腺功能减退患者、33例甲状腺增生患者以及54名年龄在35至60岁之间来自欧洲北部本地人群组的健康女性的上述指标。在所有甲状腺功能障碍形式中,患者均表现出血脂蛋白异常血症,表现为高胆固醇血症伴β胆固醇浓度升高、高甘油三酯血症,且胆固醇致动脉粥样硬化指数升至4.0及以上。血脂蛋白异常血症的体征在甲状腺毒症时最为明显,在甲状腺功能正常状态达成阶段或疾病缓解期也是如此。

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