Shatsova E N, Danilova R I, Zazhigina R N
Ter Arkh. 1988;60(9):47-50.
A study of the blood plasma content of total cholesterol in 575 healthy persons and 675 patients with diffuse toxic goiter (DTG), and the content of total lipids and triglycerides in 52 healthy persons and 132 DTG patients showed the development of adaptation hyperlipidemia in persons living long in the North. It was preserved in DTG patients irrespective of the gravity of thyrotoxicosis, stages of its therapy and the patients' age. Basing on the analysis of the level of lipid indices of erythrocytic membrane malonic dialdehyde and their refractoriness to peroxide hemolysis in 52 healthy persons and 53 DTG patients, a conclusion was made of excessive stable activation of lipid peroxidation biomembranes which can underlie the development of visceral complications.
对575名健康人和675名弥漫性毒性甲状腺肿（DTG）患者的血浆总胆固醇含量，以及52名健康人和132名DTG患者的总脂质和甘油三酯含量进行的一项研究表明，长期生活在北方的人会出现适应性高脂血症。无论甲状腺毒症的严重程度、治疗阶段和患者年龄如何，DTG患者中这种情况都会持续存在。基于对52名健康人和53名DTG患者红细胞膜丙二醛脂质指数水平及其对过氧化物溶血的耐受性的分析，得出生物膜脂质过氧化过度稳定激活的结论，这可能是内脏并发症发生的基础。
