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微流控腔室中声辐射力的建模。

Modeling the acoustic radiation force in microfluidic chambers.

作者信息

Fisher Karl A, Miles Robin

机构信息

Lawrence Livermore National Laboratory, L-333, 7000 E. Avenue, Livermore, California 94566, USA.

出版信息

J Acoust Soc Am. 2008 Apr;123(4):1862-5. doi: 10.1121/1.2839140.

DOI:10.1121/1.2839140
PMID:18396995
Abstract

A procedure is demonstrated to quantitatively evaluate the acoustic radiation forces in microfluidic particle manipulation chambers. Typical estimates of the acoustic pressure and the acoustic radiation force are based on an analytical solution for a simple one-dimensional standing wave pattern. The complexities of a typical microfluidic channel limit the usefulness of this approach. By leveraging finite elements, and a generalized equation for the acoustic radiation force, channel designs can be investigated in two and three dimensions. Calculations and experimental observations in this report and the literature, confirm these claims.

摘要

展示了一种用于定量评估微流体颗粒操纵腔室中声辐射力的方法。声压和声辐射力的典型估计基于简单一维驻波模式的解析解。典型微流体通道的复杂性限制了这种方法的实用性。通过利用有限元以及声辐射力的广义方程,可以在二维和三维中研究通道设计。本报告及文献中的计算和实验观察证实了这些说法。

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