Mori Rintaro, Shiraishi Jun, Negishi Hirokuni, Fujimura Masanori
Osaka Medical Center and Research Institute for Maternal and Child Health, Osaka, Japan.
Acta Paediatr. 2008 Jun;97(6):720-3. doi: 10.1111/j.1651-2227.2008.00759.x. Epub 2008 Apr 7.
Accurate prediction of the prognosis of infants with very low birth weight is beneficial both for their parents and for healthcare professionals.
This was a population-based study of all low-birth-weight infants admitted to neonatal units in one region in Japan. The Apgar score at 1 and 5 min and neonatal mortality were retrospectively analyzed to obtain the predictive values of the scores. The results were stratified into two categories by birth weight and three time periods (1980-1986, 1987-1993 and 1994-2000).
The predictive values improved in the later years, and therefore only the data obtained in the period 1994-2000 were used. A score of less than 5 at 5 min appears to be a good predictor of neonatal mortality in infants with a birth weight between 1500 g and 2499 g (positive likelihood ratio, 17.59 [95% confidence interval (CI) 12.68-24.40]); however, there is no evidence that the score is a good predictor of neonatal mortality in infants with very low birth weight.
In infants with a low birth weight between 1500 g and 2499 g, an Apgar score at 5 min of less than 5 is a good predictor of neonatal mortality. The score is not useful in predicting the short-term prognosis of very low-birth-weight infants.
准确预测极低出生体重婴儿的预后对其父母和医护人员均有益处。
这是一项基于日本某一地区新生儿病房收治的所有低出生体重婴儿的人群研究。回顾性分析1分钟和5分钟时的阿氏评分及新生儿死亡率,以获得评分的预测价值。结果按出生体重分为两类,并分为三个时间段(1980 - 1986年、1987 - 1993年和1994 - 2000年)。
预测价值在后期有所提高,因此仅使用1994 - 2000年期间获得的数据。对于出生体重在1500克至2499克之间的婴儿,5分钟时评分低于5似乎是新生儿死亡的良好预测指标(阳性似然比,17.59 [95%置信区间(CI)12.68 - 24.40]);然而,没有证据表明该评分是极低出生体重婴儿新生儿死亡的良好预测指标。
对于出生体重在1500克至2499克之间的低体重婴儿,5分钟时阿氏评分低于5是新生儿死亡的良好预测指标。该评分对预测极低出生体重婴儿的短期预后并无帮助。