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新型ASC(抗抑郁药敏感僵住症)品系小鼠的免疫反应

Immnune response in mice of a new strain ASC (antidepressants sensitive catalepsy).

作者信息

Alperina E L, Kulikov A V, Popova N K, Idova G V

机构信息

Laboratory for Mechanisms of Neurochemical Modulation, Institute of Physiology, Siberian Division of the Russian Academy of Medical Sciences.

出版信息

Bull Exp Biol Med. 2007 Aug;144(2):221-3. doi: 10.1007/s10517-007-0294-5.

Abstract

Inherited predisposition of ASC mice with depressive behavior to catalepsy was accompanied by a significant decrease in the immune response to sheep erythrocytes (compared to parent strains CBA and AKR). The degree of immunosuppression was highest on day 5 after immunization.

摘要

具有抑郁行为的ASC小鼠对僵住症的遗传易感性伴随着对绵羊红细胞免疫反应的显著降低(与亲本菌株CBA和AKR相比)。免疫抑制程度在免疫后第5天最高。

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