Yoon Jinhwan, Lee Seung Woo, Choi Seungchel, Heo Kyuyoung, Jin Kyeong Sik, Jin Sangwoo, Kim Gahee, Kim Jehan, Kim Kwang-Woo, Kim Heesoo, Ree Moonhor
Department of Chemistry, National Research Laboratory for Polymer Synthesis and Physics, Pohang Accelerator Laboratory, Center for Integrated Molecular Systems, Pohang University of Science and Technology (Postech), Pohang 790-784, Republic of Korea.
J Phys Chem B. 2008 May 1;112(17):5338-49. doi: 10.1021/jp711149k. Epub 2008 Apr 10.
In this study, we report the first production of two-dimensionally well-ordered molecular multilayers (i.e., with a well-defined molecular lamellar structure) based on the antiparallel beta-sheet chain conformation in thin films of a brush polypeptide, poly(S-n-hexadecyl-dl-homocysteine) (PHHC), through the use of a simple spin-coating process and the quantitative structural and property analysis of the thin films using a grazing incidence X-ray scattering technique combined with Fourier transform infrared spectroscopy and differential scanning calorimetry. These analyses provide detailed information about the structure and molecular conformation of the self-assembled lamellae in the PHHC thin film, which is not easily obtained using conventional techniques. Moreover, we used the in situ measurements carried out at various temperatures and the data analyses to establish mechanisms for the evolution of the self-assembled lamellar structures in the film and for their melting. In addition, we propose molecular structure models of the PHHC polymer molecules in the thin film at various temperatures.
在本研究中，我们报告了基于刷状多肽聚（S - 正十六烷基 - dl - 高半胱氨酸）（PHHC）薄膜中反平行β - 折叠链构象，通过简单的旋涂工艺，并使用掠入射X射线散射技术结合傅里叶变换红外光谱和差示扫描量热法对薄膜进行定量结构和性能分析，首次制备出二维有序分子多层膜（即具有明确分子层状结构）。这些分析提供了关于PHHC薄膜中自组装片层的结构和分子构象的详细信息，而这些信息使用传统技术不易获得。此外，我们利用在不同温度下进行的原位测量和数据分析，建立了薄膜中自组装层状结构的演变及其熔化机制。此外，我们还提出了不同温度下薄膜中PHHC聚合物分子的分子结构模型。
