Meister Mark G, Olsen Øystein E, de Bruyn Rose, McHugh Kieran, Marks Stephen D
Department of Paediatric Radiology, Great Ormond Street Hospital for Children NHS Trust, Great Ormond Street, London, England, UK.
Pediatr Nephrol. 2008 Jul;23(7):1157-62. doi: 10.1007/s00467-008-0784-3. Epub 2008 Apr 10.
Radiological evaluation before renal transplantation includes imaging of vascular anatomy, as thrombosis, narrowing and anomalies of the inferior vena cava (IVC) and/or iliac veins (IV) can influence the surgical technique. Most cases only require investigation with Doppler vessel ultrasonography (US), with magnetic resonance venography (MRV) reserved to clarify US findings and investigate high-risk patients. The purpose of this study was to compare these modalities in evaluating IVC and IV and correlate imaging and operative findings of patients at RTx surgery. Twenty-nine children, 21 (72%) of whom had subsequent RTx surgery, were investigated over 5 years with correlation of US and MRV in 62% (18 of 29). Technically difficult US examinations needing MRV for clarification occurred in six (21%), and normal US with anatomical variations on MRV was seen in three (10%). The anatomical variations consisted of left-sided IVC, aberrant right common femoral vein and a left IV partly draining into the azygos and renal veins. US is an excellent screening tool for evaluating vascular anatomy patency in children. MRV infrequently contributes beneficial information, is difficult to justify as a screening tool, and due to the risks of gadolinium in uraemia, should only be used on an individual patient basis.
肾移植前的放射学评估包括血管解剖成像,因为下腔静脉(IVC)和/或髂静脉(IV)的血栓形成、狭窄及异常会影响手术技术。大多数病例仅需采用多普勒血管超声检查(US),磁共振静脉血管造影(MRV)则用于明确超声检查结果及评估高危患者。本研究旨在比较这些检查方法在评估下腔静脉和髂静脉方面的效果,并将肾移植手术患者的影像学检查结果与手术发现进行关联分析。在5年时间里,对29名儿童进行了检查,其中21名(72%)随后接受了肾移植手术,62%(29名中的18名)患者的超声检查与磁共振静脉血管造影检查结果进行了关联分析。6名(21%)患者因超声检查技术难度大需要磁共振静脉血管造影来明确结果,3名(10%)患者超声检查结果正常但磁共振静脉血管造影显示存在解剖变异。解剖变异包括左侧下腔静脉、右侧股总静脉异常及左侧髂静脉部分汇入奇静脉和肾静脉。超声是评估儿童血管解剖通畅性的优秀筛查工具。磁共振静脉血管造影很少能提供有益信息,作为筛查工具难以证明其合理性,且由于尿毒症患者使用钆造影剂存在风险,因此仅应根据个体患者情况使用。