在基塔莱地区医院,自我报告的单剂量奈韦拉平预防艾滋病毒母婴传播的依从性。
Self-reported adherence to single dose nevirapine in the prevention of mother to child transmission of HIV at Kitale District Hospital.
作者信息
Bii S C, Otieno-Nyunya B, Siika A, Rotich J K
机构信息
Minisry of Health, NASCOP, Provincial AIDS/STI Co-ordinator, North Rift Province, Eldoret, Kenya.
出版信息
East Afr Med J. 2007 Dec;84(12):571-6. doi: 10.4314/eamj.v84i12.9594.
OBJECTIVES
To evaluate the uptake and adherence to single dose nevirapine among HIV positive mothers.
DESIGN
Descriptive cross-sectional study.
SETTING
The maternal and child health and family planning (MCH-FP) clinics in Kitale district hospital, Western Kenya.
SUBJECTS
HIV positive postnatal women attending MCH-FP clinic who had gone through the PMTCT programme.
RESULTS
A total of 146 respondents were recruited for this study. Most (90%) of them reported swallowing their nevirapine tablets, however only 55 swallowed their tablets within 4-12 hours before delivery. The most important factor affecting nevirapine adherence was place or delivery (p<0.05). Most (71%) of mothers who did not swallow their nevirapine delivered at home. Women attending ANC for two times or less young women under 20 years of age and single women were also less likely to swallow their nevirapine (p < 0.05). Most (91%) of the babies received their nevirapine syrup with 98% of them getting it within 72 hours of delivery. Eighty eight percent of babies who did not take their nevirapine were delivered at home. Babies whose mothers did not take their nevirapine were also more likely to miss it.
CONCLUSIONS
Self reported adherence to take home nevirapine is high. However mothers who deliver in a health facility were more likely to access nevirapine both for themselves and their babies than those delivering at home.
目的
评估HIV阳性母亲对单剂量奈韦拉平的接受情况和依从性。
设计
描述性横断面研究。
地点
肯尼亚西部基塔莱区医院的母婴健康与计划生育(MCH-FP)诊所。
研究对象
参加过预防母婴传播项目的MCH-FP诊所的HIV阳性产后妇女。
结果
本研究共招募了146名受访者。其中大多数(90%)报告已吞服奈韦拉平片,但只有55人在分娩前4至12小时内吞服。影响奈韦拉平依从性的最重要因素是分娩地点(p<0.05)。大多数(71%)未吞服奈韦拉平的母亲在家中分娩。产前检查次数为两次及以下的妇女、20岁以下的年轻妇女和单身妇女吞服奈韦拉平的可能性也较小(p<0.05)。大多数(91%)婴儿服用了奈韦拉平糖浆,其中98%在分娩后72小时内服用。88%未服用奈韦拉平的婴儿在家中分娩。母亲未服用奈韦拉平的婴儿也更有可能错过服药。
结论
自我报告的带回家奈韦拉平的依从性较高。然而,在医疗机构分娩的母亲比在家中分娩的母亲更有可能为自己和婴儿获取奈韦拉平。