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科森扎省(意大利南部卡拉布里亚大区)磷酸葡萄糖变位酶1(PGM1)基因座的遗传多态性。

Genetic polymorphism at the phosphoglucomutase 1 (PGM1) locus in Cosenza Province (Calabria--southern Italy).

作者信息

Tagarelli A, Mazzei R, Bagalà A, Bastone L, Qualtieri A, Brancati C

机构信息

Istituto per lo Studio delle Malattie Ereditarie e Carenziali-CNR, Cosenza, Italy.

出版信息

Gene Geogr. 1991 Apr-Aug;5(1-2):107-11.

PMID:1840293
Abstract

1315 school-boys of the Cosenza province (Calabria - southern Italy) were subtyped for the PGM1 locus. Three subsamples were examined, two from the Tyrrhenian and the Ionian coasts, respectively, and one from the internal part of this province. The PGM11S, PGM12S and PGM1*2F gene frequency estimates obtained for the population of the Ionian coast were significantly different from those of the tyrrhenian coast. Since the three subsamples were of similar size, estimates weighted also with the respective population sizes were calculated.

摘要

对科森扎省(意大利南部卡拉布里亚大区)的1315名男学生进行了PGM1基因座亚型分型。研究了三个子样本,其中两个分别来自第勒尼安海岸和爱奥尼亚海岸,另一个来自该省内陆地区。爱奥尼亚海岸人群的PGM11S、PGM12S和PGM1*2F基因频率估计值与第勒尼安海岸人群的估计值有显著差异。由于这三个子样本规模相似,因此还计算了根据各自人口规模加权后的估计值。

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