四种PGM1和GC亚型在撒丁岛四个省份的分布情况。
Distribution of PGM1 and GC subtypes in the four Sardinian provinces.
作者信息
Vona G, Mameli G E, Succa V
机构信息
Dipartimento di Biologia Sperimentale, Università di Cagliari, Italy.
出版信息
Gene Geogr. 1995 Apr;9(1):41-52.
Genetic polymorphism subtypes of PGM1 and GC were studied in four samples of the Sardinian population from the four Provinces of the island. The results show heterogeneity within the Sardinian population. The PGM1 alleles exhibiting the greatest variability were: PGM11S and PGM11F, with a range of .675-.724 (Nuoro - Sassari) and .072-.107 (Sassari - Nuoro) respectively. The observed GC allele frequency range were: GC1F = .029-.168 (Cagliari - Sassari); GC1S = .565-.752 (Sassari - Oristano); GC*2 = .194-.267 (Cagliari - Sassari). Sardinians showed a marked differentiation with respect to other Italian and European populations thus confirming their genetic peculiarity.
对来自该岛四个省份的四组撒丁岛人群样本进行了磷酸葡萄糖变位酶1（PGM1）和维生素D结合蛋白（GC）的基因多态性亚型研究。结果显示撒丁岛人群内部存在异质性。表现出最大变异性的PGM1等位基因是：PGM11S和PGM11F，其范围分别为0.675 - 0.724（努奥罗 - 萨萨里）和0.072 - 0.107（萨萨里 - 努奥罗）。观察到的GC等位基因频率范围为：GC1F = 0.029 - 0.168（卡利亚里 - 萨萨里）；GC1S = 0.565 - 0.752（萨萨里 - 奥里斯塔诺）；GC*2 = 0.194 - 0.267（卡利亚里 - 萨萨里）。撒丁岛人与其他意大利人和欧洲人群相比表现出明显差异，从而证实了他们的基因独特性。
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