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腹部压迫对急性肠道放射综合征影响的形态学研究。II. 30 Gy局部照射

Morphological study of the effect of abdominal compression on acute intestinal radiation syndrome. II. Local irradiation with 30 Gy.

作者信息

Kamarád V, Cernochová D, Svoboda V

机构信息

Institute of Histology and Embryology, Medical Faculty, Palacký University, Olomouc, Czechoslovakia.

出版信息

Acta Univ Palacki Olomuc Fac Med. 1991;131:125-35.

PMID:1840334
Abstract

The radioprotective effect of abdominal compression introduced by Svoboda et al. on rats exposed to local irradiation of the abdomen with 30 Gy was studied using light microscopic and histochemical methods. Irradiation combined with abdominal compression does not lead to the development of typical radiation alterations of intestinal mucosa. The protected animals retained normal structure of intestinal and colon mucosa, and unchanged epithelium with typical enzymatic equipment. Local differences in protective effect may be due to various degree of ischemization of intestinal tract.

摘要

使用光学显微镜和组织化学方法,研究了Svoboda等人提出的腹部压迫对接受30 Gy腹部局部照射的大鼠的辐射防护作用。腹部压迫联合照射不会导致肠道黏膜出现典型的辐射改变。受保护的动物肠道和结肠黏膜结构正常,上皮未改变,具有典型的酶学特征。保护作用的局部差异可能是由于肠道缺血程度不同所致。

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