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A highly efficient and selective synthesis of 1,2,3-triazole linked saccharide nucleosides via "click chemistry".

作者信息

Ding Haixin, Yang Ruchun, Song Yang, Xiao Qiang, Wu Jun

机构信息

Jiangxi Key Laboratory of Organic Chemistry, Jiangxi Science & Technology Normal University, Jiangxi, PR China.

出版信息

Nucleosides Nucleotides Nucleic Acids. 2008 Apr;27(4):368-75. doi: 10.1080/15257770801944055.

Abstract

A series of 1,2,3-triazole linked saccharide nucleosides were synthesized in high yield and selectivity via "click chemistry" of the 3'-azido-2'-deoxythymidine and the propargyl carbohydrates. [image omitted].

摘要

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