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髋关节置换患者在正常行走过程中产生的磨损路径对磨损率的影响。

The influence of wear paths produced by hip replacement patients during normal walking on wear rates.

作者信息

Bennett Damien, Humphreys Lee, O'Brien Seamus, Kelly Connor, Orr John, Beverland David E

机构信息

Outcome Assessment Unit, Musgrave Park Hospital, Belfast, Northern Ireland.

出版信息

J Orthop Res. 2008 Sep;26(9):1210-7. doi: 10.1002/jor.20583.

DOI:10.1002/jor.20583
PMID:18404653
Abstract

Variation in wear paths is known to greatly affect wear rates in vitro, with multidirectional paths producing much greater wear than unidirectional paths. This study investigated the relationship between multidirectional motion at the hip joint, as measured by aspect ratio, sliding distance, and wear rate for 164 hip replacements. Kinematic input from three-dimensional gait analysis was used to determine the wear paths. Activity cycles were determined for a subgroup of 100 patients using a pedometer study, and the relationship between annual sliding distance and wear rate was analyzed. Poor correlations were found between both aspect ratio and sliding distance and wear rate for the larger group and between annual sliding distance and wear rate for the subgroup. However, patients who experienced a wear rate <0.08 mm/year showed a strong positive correlation between the combination of sliding distance, activity levels, and aspect ratio and wear rate (adjusted r(2) = 55.4%). This group may represent those patients who experience conditions that most closely match those that prevail in simulator and laboratory tests. Although the shape of wear paths, their sliding distance, and the number of articulation cycles at the hip joint affect wear rates in simulator studies, this relationship was not seen in this clinical study. Other factors such as lubrication, loading conditions and roughness of the femoral head may influence the wear rate.

摘要

磨损路径的变化在体外已知会极大地影响磨损率,多向路径产生的磨损比单向路径大得多。本研究调查了164例髋关节置换术中,通过纵横比、滑动距离测量的髋关节多向运动与磨损率之间的关系。使用三维步态分析的运动学输入来确定磨损路径。通过计步器研究确定了100例患者亚组的活动周期,并分析了年滑动距离与磨损率之间的关系。对于较大的组,纵横比和滑动距离与磨损率之间以及亚组的年滑动距离与磨损率之间均发现相关性较差。然而,磨损率<0.08 mm/年的患者在滑动距离、活动水平和纵横比的组合与磨损率之间显示出强正相关(调整后r² = 55.4%)。该组可能代表那些经历的情况与模拟器和实验室测试中普遍存在的情况最接近匹配的患者。尽管在模拟器研究中,磨损路径的形状、其滑动距离以及髋关节的关节活动周期数量会影响磨损率,但在这项临床研究中未观察到这种关系。其他因素,如润滑、加载条件和股骨头粗糙度,可能会影响磨损率。

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