系统性红斑狼疮（SLE）的肺部表现，特别提及高分辨率CT（HR CT）

Pulmonary manifestations in systemic lupus erythematosus (SLE) with special reference to HR CT.

作者信息

Kakati S, Doley B, Pal S, Deka U J

机构信息

Department of Medicine, Assam Medical College, Dibrugarh, Assam.

出版信息

J Assoc Physicians India. 2007 Dec;55:839-41.

PMID:18405129

Abstract

AIMS AND OBJECTIVES

To evaluate whether CT helps in the early diagnosis of pulmonary manifestations in SLE. 2. To study the pulmonary involvement and determine the incidence and type of pulmonary involvement.

MATERIALS AND METHODS

Thirty eight patients fulfilling ACR classification criteria for SLE were studied. Chest X-ray, pulmonary function tests (PFT), HRCT scan thorax were done. Investigations were done to detect other organ involvement. Patients with known interstitial lung disease (occupational hazard) or pregnant females were excluded.

RESULTS

Clinical signs and symptoms referable to pulmonary involvement were present in 9 patients (23.68%). HRCT thorax detected abnormalities in 21 patients (55.26%); pulmonary function abnormalities were present in 11 patients (28.95%) and plain X-ray chest abnormalities were present in 7 patients (18.42%). Out of 38 patients pulmonary involvement was present in 22 (57.89%) cases and HRCT thorax findings were present in 21 (95.45%) of them.

CONCLUSION

Pulmonary involvement is present in a significant number of SLE patients, who are often asymptomatic, with normal chest X-ray or normal PFT. HRCT scan thorax could diagnose the pulmonary involvement in asymptomatic patients with normal chest X-ray and uncertain PFT.

摘要

目的与目标

评估CT是否有助于系统性红斑狼疮（SLE）肺部表现的早期诊断。2. 研究肺部受累情况，确定肺部受累的发生率及类型。

材料与方法

对38例符合美国风湿病学会（ACR）SLE分类标准的患者进行研究。进行了胸部X线检查、肺功能测试（PFT）、胸部高分辨率CT（HRCT）扫描。还进行了检查以检测其他器官受累情况。排除已知间质性肺病（职业性危害）患者或孕妇。

结果

9例患者（23.68%）出现了与肺部受累相关的临床体征和症状。胸部HRCT检查发现21例患者（55.26%）有异常；11例患者（28.95%）存在肺功能异常，7例患者（18.42%）胸部X线平片有异常。38例患者中，22例（57.89%）存在肺部受累，其中21例（95.45%）有胸部HRCT检查结果。