Pettersen Michael D, Du Wei, Skeens Mary Ellen, Humes Richard A
Carman and Ann Adams Department of Pediatrics, Wayne State University School of Medicine, Detroit, Michigan, USA.
J Am Soc Echocardiogr. 2008 Aug;21(8):922-34. doi: 10.1016/j.echo.2008.02.006. Epub 2008 Apr 11.
Decision making in the care of pediatric patients with congenital and acquired heart disease remains reliant on detailed measurements of cardiac structures using 2-dimensional echocardiography. Calculated z scores are often used to normalize these measurements to the patient's body size. Existing normal data in the literature are limited by small sample size, small numbers of measured cardiac structures, and inadequate data for the calculation of z scores. Accordingly, we sought to develop normative data in a large pediatric cohort using modern echocardiographic equipment from which z scores could be calculated.
Two-dimensional and M-mode echocardiography was performed in 782 patients ranging in age from 1 day to 18 years. Measurements were made of 21 individual cardiac structures. Regression equations were derived to relate the size of the various cardiac structures to body surface area. Data are presented graphically, and regression equations are derived relating cardiac dimension to body surface area.
The presented data will allow the calculation of z scores for echocardiographically measured cardiac structures. This information will be valuable for clinicians caring for infants and children with known or suspected cardiac disease.
先天性和后天性心脏病患儿的护理决策仍依赖于使用二维超声心动图对心脏结构进行详细测量。计算得到的z值常被用于将这些测量值根据患者的体型进行标准化。文献中现有的正常数据受到样本量小、测量的心脏结构数量少以及计算z值的数据不足的限制。因此，我们试图利用现代超声心动图设备在一个大型儿科队列中建立规范数据，从中可以计算z值。
对782例年龄从1天到18岁的患者进行二维和M型超声心动图检查。对21个独立的心脏结构进行测量。推导回归方程以将各种心脏结构的大小与体表面积相关联。数据以图表形式呈现，并推导了将心脏尺寸与体表面积相关联的回归方程。
所呈现的数据将允许计算超声心动图测量的心脏结构的z值。这些信息对于照顾患有已知或疑似心脏病的婴幼儿的临床医生将是有价值的。
