Trends Endocrinol Metab. 1997 Jan-Feb;8(1):20-5. doi: 10.1016/s1043-2760(96)00204-4.
The potential risk factors for thyroid carcinoma development include genetic predisposition, exposure to therapeutic or environmental ionizing radiation, residence in areas of iodine deficiency or excess, history of preexisting benign thyroid disease, as well as hormonal and reproductive factors. In this review, we analyze some of the epidemiological data, as well as the possible molecular mechanisms by which certain environmental and genetic factors might predispose to thyroid tumorigenesis. (c) 1997, Elsevier Science Inc. (Trends Endocrinol Metab 1997; 8:20-25).
甲状腺癌发生的潜在危险因素包括遗传易感性、治疗或环境电离辐射暴露、碘缺乏或过量地区居住、既往存在良性甲状腺疾病史、以及激素和生殖因素。在这篇综述中，我们分析了一些流行病学数据，以及某些环境和遗传因素可能导致甲状腺肿瘤发生的潜在分子机制。（c）1997，Elsevier Science Inc.（趋势内分泌代谢 1997；8:20-25）。
