Anglin Deidre M, Cohen Patricia R, Chen Henian
Department of Psychiatry, Columbia University, College of Physicians and Surgeons, United States.
Schizophr Res. 2008 Aug;103(1-3):143-50. doi: 10.1016/j.schres.2008.02.016. Epub 2008 Apr 14.
Early childhood experiences influence the capacity for healthy social and emotional development. The present study uses longitudinal data to determine whether early maternal separation predicted the subsequent development of schizotypal personality disorder (SPD) symptoms assessed repeatedly from early adolescence over the following 20 years. Within this community sample (N=766), multilevel linear regression analyses revealed the duration of separation from mother in the first 2 years of life predicted elevated SPD symptoms. This relationship was specific to children with mother-reported early angry emotional behavior. These results provide support for the role of early childhood psychosocial risk factors in the development of subsequent schizophrenia spectrum symptoms in emotionally vulnerable children.
幼儿期经历会影响健康的社交和情感发展能力。本研究使用纵向数据来确定早期母婴分离是否能预测随后20年从青少年早期开始反复评估的分裂型人格障碍（SPD）症状的发展。在这个社区样本（N = 766）中，多层次线性回归分析显示，生命最初两年与母亲分离的时长能预测更高的SPD症状。这种关系在母亲报告有早期愤怒情绪行为的儿童中尤为明显。这些结果为幼儿期心理社会风险因素在情感脆弱儿童随后出现精神分裂症谱系症状过程中的作用提供了支持。
