Merlo M, Nazzaro P, Manzari M, Pirrelli A
Servizio Ipertensione Arteriosa, Università di Bari.
Boll Soc Ital Biol Sper. 1991 Dec;67(12):1007-14.
In order to evaluate a peculiar hemodynamic and psychophysiological reactivity in hypertensive-diabetics, a male population of mild essential hypertensives and mild NID hypertensive-diabetics underwent a session of tests:Arithmetic, Sacks', Cold Pressor, Hand-grip, preceded and followed by a 10' recovery period, Valsalva Manoeuver, Beat to beat, Tilt table. Along the entire session, by means of a beat to beat, non invasive computerized system, we measured some pressure, hemodynamic, and extra-cardiovascular variables. The obtained findings seem to suggest a sympathetic hyperreactivity both in HD and in H. In HD it has a particular "tropism" for peripheral vascular bed, as showed by vascular resistances and peripheral temperature responsivity; on the other hand the cardiac contractility index is more depressed than in H, suggesting that in HD, cardiac and pressor responses might be influenced by some mechanisms whose nature seem related to neither functional damage nor hemodynamic adjustments. The different profiles of the two populations seem to confirm the utility of this kind of hemodynamic, non invasive evaluation in all the pathologies where Autonomic Nervous System is involved, in order to obtain a better diagnosis approach and therapeutic treatment.