Suppr超能文献

经半后矢状位肛门直肠成形术对肛门闭锁合并直肠尿道瘘或直肠前庭瘘进行一期矫治。

Single-stage correction of imperforate anus with a rectourethral or a rectovestibula fistula by semi-posterior sagittal anorectoplasty.

作者信息

Zheng Shan, Xiao Xianmin, Huang Yanlei

机构信息

Department of Pediatric Surgery, Children's Hospital of Fudan University, 183 Feng Lin Road, 200032, Shanghai, People's Republic of China.

出版信息

Pediatr Surg Int. 2008 Jun;24(6):671-6. doi: 10.1007/s00383-008-2154-4. Epub 2008 Apr 12.

Abstract

The aim of this study was to evaluate the clinical advantages of a single-stage correction of imperforate anus with a rectourethral or a rectovestibula fistula in neonates by a semi-posterior sagittal anorectoplasty (PSARP). The medical records of 38 neonates (5 females and 33 males) who had imperforate anus with a rectourethral or a rectovestibula fistula were reviewed and analyzed in Children's Hospital of Fudan University between January 2004 and July 2007. All patients had an anorectal malformation but without obvious sacral dysplasia. The first group had a single-stage PSARP without a colostomy. All neonates were full-term without severe cardiac, renal anomalies or severe abdominal distension. The second group had a staged Peña procedure; the neonates were not suitable for a single-stage PSARP because of severe abdominal distention or cardiac, renal anomalies. A transverse colostomy was performed, followed 3-6 months later by the Peña procedure, and colostomy closure 2 months thereafter. The congenital anomalies, fetal age, birth weight, time and age of the definitive operation, complications, length of hospital stay, cost, and postoperative bowel movements were analyzed between these two groups. Among the 38 patients, 22 had a single-stage definitive operation and 16 had a staged pull-through procedure. There were significant differences in congenital anomalies between the two groups (P = 0.0314), but no statistically significant differences between the fetal ages, weight at birth, and time and age at the time of the definitive operation (P > 0.05). One patient in the first group had intestinal obstruction and intestinal perforation. For the second group, early complications were related to the colostomy. At after 3 years postoperatively, 9 patients in the first group and 12 patients in the second group were followed-up and all had positive voluntary bowel movements. There were no statistically significant differences in soiling and constipation grades between the two groups. The total length of hospital stay was 12.06 +/- 0.85 and 33.85 +/- 0.94 days and the cost was 10,681.1 +/- 1,759.5 and 27,355.9 +/- 1,952.0 RMB for the first and second groups, respectively. There was a statistically significant difference in the total length of hospital stay and cost between the two groups (P < 0.0001); however, there were no statistically significant differences in the length of hospital stay and cost during the definitive operation between the two groups (P > 0.05). This retrospective study shows that it is feasible for correction of imperforate anus with a rectourethral or a rectovestibula fistula in neonates using a modified PSARP without a colostomy.

摘要

本研究旨在评估采用半后矢状肛门直肠成形术(PSARP)对患有直肠尿道瘘或直肠前庭瘘的新生儿进行一期肛门闭锁矫正术的临床优势。回顾并分析了2004年1月至2007年7月在复旦大学附属儿科医院就诊的38例患有直肠尿道瘘或直肠前庭瘘的肛门闭锁新生儿(5例女性,33例男性)的病历。所有患者均患有肛门直肠畸形,但无明显骶骨发育不良。第一组采用一期PSARP且未行结肠造口术。所有新生儿均为足月儿,无严重心脏、肾脏异常或严重腹胀。第二组采用分期Peña手术;由于严重腹胀或心脏、肾脏异常,这些新生儿不适合一期PSARP。先行横结肠造口术,3 - 6个月后行Peña手术,此后2个月关闭结肠造口。分析了两组之间的先天性异常、胎龄、出生体重、确定性手术时间和年龄、并发症、住院时间、费用以及术后排便情况。38例患者中,22例行一期确定性手术,16例行分期拖出术。两组之间先天性异常存在显著差异(P = 0.0314),但胎龄、出生体重以及确定性手术时间和年龄之间无统计学显著差异(P > 0.05)。第一组有1例患者发生肠梗阻和肠穿孔。对于第二组,早期并发症与结肠造口有关。术后3年,对第一组的9例患者和第二组的12例患者进行随访,所有患者自主排便均正常。两组之间在便污和便秘分级方面无统计学显著差异。第一组和第二组的总住院时间分别为12.06±0.85天和33.85±0.94天,费用分别为10681.1±1759.5元和27355.9±1952.0元。两组之间总住院时间和费用存在统计学显著差异(P < 0.0001);然而,两组在确定性手术期间的住院时间和费用无统计学显著差异(P > 0.05)。这项回顾性研究表明,采用改良的PSARP且不行结肠造口术对患有直肠尿道瘘或直肠前庭瘘的新生儿进行肛门闭锁矫正术是可行的。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验