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洛努瓦-本索德综合征:肥胖症的一种罕见定位。

Launois-Bensaude Syndrome: an unusual localization of obesity disease.

作者信息

Verna Giovanni, Kefalas Nicola, Boriani Filippo, Carlucci Salvatore, Choc Ingrid, Bocchiotti Maria Alessandra

机构信息

Department of Plastic Reconstructive and Aesthetic Surgery, University of Turin, Turin, Italy.

出版信息

Obes Surg. 2008 Oct;18(10):1313-7. doi: 10.1007/s11695-008-9502-2. Epub 2008 Apr 12.

Abstract

BACKGROUND

Launois-Bensaude syndrome is a rare pathology consisting of adipose masses symmetrically distributed mainly in the superior part of the body. Men are especially affected between age of 30 and 60 as well as chronic alcohol abusers. Etiopathogenesis is attributable to mutations or deletions of mitochondrial DNA, and alcohol is a possible cofactor.

METHODS

The current treatment of the disease is described based on the authors' experience. Four cases treated in our department are retrospectively reviewed regarding comorbidities and type of surgery performed.

RESULTS

A relevant and long-lasting reduction of fat bulges has been obtained in all cases with no major complications except for a mild anemia.

CONCLUSION

Launois-Bensaude syndrome causes a functional rather than esthetic concern due to the peculiar localization of fat bulges. Currently, the only effective therapy is surgery, through lipectomy or liposuction of adipose bulges.

摘要

背景

洛努瓦-本索德综合征是一种罕见的病症,其特征为脂肪团主要对称分布于身体上部。男性在30至60岁之间以及慢性酗酒者尤其易受影响。病因发病机制归因于线粒体DNA的突变或缺失,酒精可能是一个辅助因素。

方法

根据作者的经验描述了该疾病的当前治疗方法。回顾性分析了我科治疗的4例患者的合并症及所施行的手术类型。

结果

所有病例均实现了脂肪凸起的显著且持久的减少,除轻度贫血外无重大并发症。

结论

由于脂肪凸起的特殊定位,洛努瓦-本索德综合征引起的是功能方面而非美观方面的问题。目前,唯一有效的治疗方法是通过脂肪切除术或吸脂术去除脂肪凸起进行手术治疗。

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