Krysiak Robert, Okopień Bogusław, Herman Zbigniew Stanisław
Klinika Chorób Wewnetrznych i Farmakologii Klinicznej Katedry Farmakologii Slaskiego Uniwersytetu Medycznego w Katowicach.
Przegl Lek. 2007;64(7-8):515-20.
Hypophysitis is a rare endocrine disorder with a female predilection affecting mainly young women during late pregnancy and in the postpartum period. The clinical, histopathological and morphological findings and the association of the disease with other autoimmune disorders allow most cases of hypophysitis to be included among the autoimmune diseases. This potentially life-threatening condition should be suspected especially in women of reproductive age who present with hypopituitarism or evidence of pituitary mass-induced headaches and visual symptoms. The natural history of hypophysitis is variable. At the present time, the treatment is only symptomatic but there is no absolute agreement among endocrinologists about the optimal management of this condition. In this review, aetiology, symptoms, clinical classification, diagnosis and treatment of hypophysitis are discussed with a special emphasis on the most recent literature.
垂体炎是一种罕见的内分泌疾病，女性更易患病，主要影响妊娠晚期和产后的年轻女性。该疾病的临床、组织病理学和形态学表现以及与其他自身免疫性疾病的关联，使得大多数垂体炎病例可归为自身免疫性疾病。这种潜在的危及生命的疾病尤其应在出现垂体功能减退或有垂体肿块引起的头痛和视觉症状的育龄妇女中引起怀疑。垂体炎的自然病程各不相同。目前，治疗仅为对症治疗，但内分泌学家对于该疾病的最佳管理尚无绝对一致的意见。在这篇综述中，将讨论垂体炎的病因、症状、临床分类、诊断和治疗，并特别强调最新文献。
