Leone A, Magrini A, Pietroiusti A, Vinci F
lstituto di Medicina del Lavoro, Università Cattolica del Sacro Cuore, Roma.
G Ital Med Lav Ergon. 2007 Jul-Sep;29(3 Suppl):843-4.
Elaborating and proposing a model of behaviour which is useful for any occupational doctor of a hospital in the management of the people exposed to biological risk, with the aim of preventing or early diagnosing neoplasias caused by cancerogenic infective agents.
This study was conducted analyzing the literature data regarding biohazard work accidents which happened in health environment and the scientific evidence of the causal relationship between infective agents and development of neoplasias.
Data in literature show that the biohazard work accidents are very numerous and there is high percentage of sub-communication of them; many infective agents that the health workers can get in contact with, after biohazard biological accidents, are cancerogenic: HBV, HCV, HIV, HP belong to group 1 of IARC classification.
Health workers exposed to biological risk and in particular those who got in contact with infective biological liquids can be considered at risk of neoplasia development; for this reason, we propose a three phases behaviour model: 1. Biological risk accidents prevention; 2. Prevention of infective disease after an accident; 3. Neoplasia prevention and/or early diagnosis after the development of the infective disease.
阐述并提出一种行为模式，该模式对医院的任何职业医生在管理接触生物风险的人员时有用，旨在预防或早期诊断由致癌感染因子引起的肿瘤。
本研究通过分析健康环境中发生的生物危害工作事故的文献数据以及感染因子与肿瘤发生之间因果关系的科学证据来进行。
文献数据表明，生物危害工作事故数量众多且报告率较低；卫生工作者在生物危害生物事故后可能接触到的许多感染因子具有致癌性：乙肝病毒、丙肝病毒、艾滋病毒、幽门螺杆菌属于国际癌症研究机构分类的第1组。
接触生物风险的卫生工作者，尤其是那些接触过感染性生物液体的人员，可被视为有发生肿瘤的风险；因此，我们提出一个三阶段行为模式：1. 预防生物风险事故；2. 事故后预防感染性疾病；3. 在感染性疾病发生后预防肿瘤和/或早期诊断。
